南京市发现感染札幌病毒致老年人腹泻

发布时间：2018-07-17 04:12

【摘要】：目的探讨应用分子生物学检测老年人腹泻病因的临床评价。方法随机收集2011年1~6月在南京某医院腹泻门诊就诊并临床诊断病毒性腹泻的60岁以上老年人的粪便20份,对诺如病毒、札幌病毒、轮状病毒、肠腺病毒和星状病毒进行分子生物学检测,并将检测结果与临床诊断进行比对,用于指导用药和治疗。结果 20份随机样中共检测到13份阳性,其中有5份诺如病毒,4份轮状病毒,2份肠腺病毒,1份星状病毒,1份札幌病毒,病毒感染阳性率高达65%,加上由于技术原因不能检测到的病毒,该结果说明临床判断的准确性很高。结论确定病原后采取支持疗法,病人康复,避免了抗生素的使用。另外,札幌病毒感染老年人致腹泻在南京是首次报道。
[Abstract]:Objective to investigate the clinical evaluation of molecular biology in the diagnosis of diarrhea in the elderly. Methods from January to June 2011, 20 feces from elderly patients over 60 years old who had been diagnosed with viral diarrhea were randomly collected from an outpatient clinic of a hospital in Nanjing from January to June, 2011, and treated with norovirus, Sapporo virus and rotavirus. Enteroadenovirus and stellate virus were detected by molecular biology and compared with clinical diagnosis. Results A total of 13 positive samples were detected in 20 random samples, of which 5 were norovirus, 4 rotavirus, 2 enteroadenovirus, 1 stellate virus and 1 Sapporo virus. The positive rate of virus infection is as high as 65%, plus the virus that can not be detected due to technical reasons, the results show that the accuracy of clinical judgment is very high. Conclusion the patients were cured by supportive therapy and the use of antibiotics was avoided. In addition, diarrhea caused by Sapporo virus infection in the elderly is the first reported in Nanjing.
【作者单位】：南京市疾病预防控制中心;江苏省疾病预防控制中心;东南大学附属中大医院;
【基金】：国家科技支撑计划(No.2011BAK21B00) 南京市科技发展重点项目(No.ZKX09033)
【分类号】：R512.5

【共引文献】