南京市2013年MSM的HIV新发感染情况分析

发布时间：2018-08-08 11:11

【摘要】：目的了解南京市男男性行为人群(MSM)艾滋病病毒(HIV)的感染状况,估算HIV在该人群中的新发感染率。方法通过滚雪球方法在南京市招募到656例MSM,进行问卷调查和HIV血清学检测;检出的HIV阳性样本,再应用BED HIV IgG捕获酶免疫法(BED-CEIA)检出其中的新发感染样本,进而估算该人群的HIV新发感染率。结果 656名调查对象平均年龄(31.12±10.80)岁(16~78岁);未婚占67.8%;本省占68.3%;在本地居住时间2年以上占79.4%;大专及以上占57.3%。认同自己为同性恋者占62.5%,认同自己为双性恋者占31.7%。寻找性伴场所最多的为网络/论坛,占52.1%。其次为酒吧/会所,占16.0%。93.3%的调查对象掌握艾滋病预防控制知识;58.5%的调查对象在近6个月内与同性发生过无保护性肛交性行为。656份样本检测出HIV阳性64份,HIV感染率为9.76%。进行BED检测的59份HIV阳性样本中,20份被判定为新发感染,感染者中新发感染比例为33.90%;校正公式计算的HIV新发感染率为6.39%[95%可信区间(CI):3.03%~9.76%]。HIV阳性病例中,判定为新发感染的病例CD+4T淋巴细胞计数均值高于判定为长期感染病例,均值差异有统计学意义。结论南京市MSM的HIV感染率处于较高水平,新发感染情况不容乐观,必须加大综合干预力度,促进该人群改变行为。
[Abstract]:Objective to investigate the status of (MSM) HIV (HIV) infection in men who have sex with men in Nanjing and estimate the new infection rate of HIV in this population. Methods A total of 656 MSMs were recruited in Nanjing by snowball-rolling method, and the positive samples of HIV were detected by questionnaire and HIV serology, and the newly infected samples were detected by BED HIV IgG capture enzyme immunoassay (BED-CEIA). The new infection rate of HIV in this population was estimated. Results the average age of 656 subjects was (31.12 卤10.80) years old (1678 years old), 67.8% of them were unmarried, 68.3% of them were unmarried, 79.4% of them lived in local areas for more than 2 years, and 57.3% were college students. Identify yourself as gay 62.5, identify yourself as bisexual 31.7. Internet / forum is the most place to find sex partners, accounting for 52.1%. The next was bar / clubhouse, accounting for 16.0% and 93.3%. 58.5% of the subjects had unprotected anal sex with the same sex in the past 6 months, and 64 of them had unprotected anal sex with the same sex in the past 6 months. The infection rate of HIV positive 64 cases was 9.76%. Of the 59 HIV positive samples tested by BED, 20 were determined to be new infections, and the proportion of new infections was 33.900.The new HIV infection rate calculated by the corrected formula was 6.39% [95% confidence interval (CI): 3.039.76%] .HIV positive cases. The mean value of CD4T lymphocyte count in newly infected patients was higher than that in long-term infection cases, and the difference was statistically significant. Conclusion the HIV infection rate of MSM in Nanjing is at a high level and the situation of new infection is not optimistic. It is necessary to increase the comprehensive intervention to promote the behavior change of this population.
【作者单位】：南京市疾病预防控制中心;江苏省疾病预防控制中心;
【分类号】：R512.91

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