周口市HIV阳性孕产妇接受预防母婴传播干预措施情况及影响因素分析

发布时间：2018-08-16 09:57

【摘要】：目的了解周口市预防艾滋病母婴传播措施落实情况,评价预防效果。方法对2003-2012年发现的140例HIV阳性孕产妇及其接受预防艾滋病母婴传播干预措施进行分析。结果 140例孕产妇中,53例选择自愿人工终止妊娠,占37.9%,87例选择分娩,占62.1%,多因素Logistic回归分析显示,终止妊娠比例随着孕产妇年龄增大而增高(OR=1.084;95%CI:1.005~1.170),随产次的增多而降低(OR=0.376;95%CI:0.143~0.991),随HIV初检孕周增加而降低(OR=0.933;95%CI:0.904~0.963);87例选择分娩孕产妇64人应用抗病毒药物预防艾滋病母婴传播,用药率为73.6%,所分娩活产婴儿86名,81名儿童服用艾滋病抗病毒治疗药物,服药率94.2%,HIV初检孕周越早,母亲用药率越高(χ2=8.8,P0.05);86名儿童18月龄HIV检测显示,HIV阳性3人,阳性率3.5%。结论周口市自2003年开展预防艾滋病母婴传播工作以来,各项措施落实到位,工作成效明显;孕期发现HIV感染,是落实预防艾滋病母婴措施的关键环节,做好母婴传播工作,必须将HIV检测工作的重点放在孕期阶段,充分发挥三级妇幼保健网络作用,提高孕期检测率,及早发现孕期HIV感染者,及早发现HIV阳性育龄妇女怀孕情况,切实做到早检测、早发现、早干预。
[Abstract]:Objective to investigate the implementation of measures to prevent mother-to-child transmission of AIDS in Zhoukou City and evaluate the effect of prevention. Methods 140 cases of HIV positive pregnant women from 2003 to 2012 and their intervention measures to prevent mother-to-child transmission of AIDS were analyzed. Results 53 of 140 pregnant women chose voluntary artificial termination of pregnancy, 37. 9% of 87 women chose to deliver, accounting for 62. 1%. Multivariate Logistic regression analysis showed that. The proportion of termination of pregnancy increased with the increase of age of the pregnant and parturient (OR 1.084: 95CI: 1.0051.170), decreased with the increase of the number of births (OR0.37695 CI: 0.143 / 0.991), and decreased with the increase of the gestational week of HIV (OR.0.933 / 95: CI0.9040.963). 87 cases of pregnant women who chose to use antiviral drugs to prevent mother-to-child transmission of HIV / AIDS were selected for delivery. The drug use rate was 73.6. 86 infants born alive and 81 children were treated with HIV antiviral drugs. The earlier the pregnant week was, the higher the rate of medication was (蠂 2 8. 8% P 0.05). The HIV test of 86 children at 18 months old showed that 3 children were HIV positive, and the positive rate was 3. 5%. Conclusion since the prevention of mother-to-child transmission of AIDS in Zhoukou City in 2003, the measures have been put in place and the results of the work have been obvious. The discovery of HIV infection during pregnancy is the key link in the implementation of the measures to prevent mother-to-child transmission of AIDS, and the work of mother-to-child transmission is well done. It is necessary to put the emphasis of HIV detection on the pregnant stage, to give full play to the role of three-level maternal and child health care network, to improve the pregnancy detection rate, to find out early pregnant women infected with HIV during pregnancy, and to detect the pregnant situation of women of childbearing age with positive HIV as early as possible, so as to effectively achieve early detection. Early discovery, early intervention.
【作者单位】：周口市疾病预防控制中心;
【分类号】：R512.91

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