深圳市妊娠梅毒及相关不良妊娠结局的疾病负担估计

发布时间：2018-10-15 18:07

【摘要】：目的评估深圳市2002-2012年妊娠梅毒及其相关不良妊娠结局的疾病负担的变化趋势。方法收集预防与控制梅毒母婴传播项目的监测资料,以及文献资料中的相关数据,运用妊娠梅毒及梅毒相关不良妊娠结局疾病负担估计模型进行估计。结果项目实施后,孕妇人群参加≥1次的产前保健比例、接受梅毒血清学检测的比例和妊娠梅毒患者获得足量抗梅毒治疗的比例,分别从2002年的74.86%、89.75%和84.13%上升至2012年的89.74%,97.23%和96.06%;妊娠梅毒和梅毒相关不良妊娠结局的疾病负担在2007年达到高峰,2008-2012年呈下降趋势。若未实施任何干预项目,深圳市2002-2012年间将发生4676例梅毒相关不良妊娠结局;由于项目的实施,共避免了2974例不良妊娠结局的发生。2012年全市梅毒相关不良妊娠结局发生数,与消除先天梅毒计划目标估计数相差7例。结论预防与控制梅毒母婴传播项目的实施,有效地减少了妊娠梅毒和梅毒相关不良妊娠结局的疾病负担,基本达到全球关于消除先天梅毒的目标。
[Abstract]:Objective to evaluate the trend of disease burden of syphilis and its associated adverse pregnancy outcomes in Shenzhen from 2002 to 2012. Methods the monitoring data of prevention and control of syphilis transmission from mother to child were collected and the related data were collected and estimated by using the disease burden estimation model of syphilis and syphilis related adverse pregnancy outcome. Results after the implementation of the project, the proportion of pregnant women who participated in the antenatal care more than once, the proportion of syphilis serological tests and the proportion of pregnant syphilis patients receiving adequate anti-syphilis treatment, From 74.86% and 84.13% in 2002 to 89.74% and 96.06% in 2012, respectively, the disease burden of syphilis and syphilis related adverse pregnancy outcome reached its peak in 2007, and decreased in 2008-2012. Without any intervention, 4676 syphilis related adverse pregnancy outcomes will occur in Shenzhen between 2002 and 2012; 2974 adverse pregnancy outcomes will be avoided as a result of the implementation of the project, and the number of syphilis related adverse pregnancy outcomes in the city in 2012. There was a difference between 7 cases and the target estimate for the elimination of congenital syphilis. Conclusion the implementation of the project on prevention and control of mother-to-child transmission of syphilis can effectively reduce the disease burden of syphilis and syphilis related adverse pregnancy outcomes, and basically achieve the goal of eliminating congenital syphilis worldwide.
【作者单位】：深圳市慢性病防治中心;
【基金】：广东省医学科研基金项目(B2013357)~~
【分类号】：R759.15

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