2006—2012年贺州市预防艾滋病母婴传播干预措施状况分析

发布时间：2018-10-30 18:58

【摘要】：目的了解贺州市孕产期艾滋病抗体检测、感染孕产妇及感染孕产妇母子抗艾滋病病毒药物应用与检测状况及变化趋势。方法利用国家预防艾滋病母婴传播管理信息网络直报系统,收集和整理贺州市2006—2012年孕产期艾滋病抗体、CD+4T淋巴细胞、病毒载量等检测信息、HIV感染孕产妇孕期、产时以及所生儿童应用抗逆转录病毒药物等相关信息。对相关数据进行描述性分析和年度趋势变化分析。结果 2006—2012年贺州市共有130 743例孕产妇接受艾滋病抗体检测,其中孕产妇HIV抗体检测率从2006年的88.68%上升至2012年的99.96%。7年中,贺州市共发现230例HIV感染孕产妇。2006—2012年分别有67.86%、70.59%、82.05%、82.14%、97.30%、100%和100%的感染孕产妇应用了抗病毒药物,并呈逐年上升趋势(χ2=6.30,P0.05),感染产妇孕28周前(含28周)开始应用三联方案比例也呈逐年上升趋势;感染产妇所生婴儿抗逆转录病毒药物应用比例自2010年均达到100%。结论孕期抗体检测比例仍有待进一步提高。尽管感染孕产妇及所生婴儿抗病毒药物应用比例逐年上升,但感染产妇在孕早期抗病毒药物应用比例比较低,需要进一步提高孕早期抗体检测比例及感染产妇在孕早期抗病毒药物应用比例,从而减少母婴传播的风险。
[Abstract]:Objective to investigate the status and trend of anti-HIV drugs used and detected in pregnant and pregnant women and infected pregnant women in Hezhou City. Methods the information of CD 4T lymphocytes, CD 4T lymphocytes and viral load of pregnant women in Hezhou City during pregnancy and delivery period from 2006 to 2012 were collected and sorted by the National Network Direct reporting system for the Prevention of Mother-to-Child Transmission of AIDS. The pregnant women were infected with HIV during pregnancy. Information related to the use of antiretroviral drugs at birth and in children born. Carry on descriptive analysis and annual trend change analysis to relevant data. Results A total of 130,743 pregnant women were tested for HIV antibody in Hezhou City from 2006 to 2012. The HIV antibody detection rate of pregnant women increased from 88.68% in 2006 to 99.96.7 years in 2012. A total of 230 pregnant and lying-in women with HIV infection were found in Hezhou City. From 2006 to 2012, 67.86% of the pregnant and lying-in women with HIV were 70.59 and 82.05%, and 82.14%, 97.30% and 100% of the infected pregnant and lying-in women received antiviral drugs, respectively, from 2006 to 2012. The proportion of pregnant women who began to use triple regimen before 28 weeks of pregnancy (including 28 weeks) showed an increasing trend year by year. The proportion of antiretrovirals used in infants born to infected women has reached 100 since 2010. Conclusion the ratio of antibody detection in pregnancy needs to be further improved. Although the proportion of antiviral drugs used in infected pregnant women and their babies has increased year by year, the proportion of infected women using antiviral drugs in early pregnancy is relatively low. In order to reduce the risk of mother-to-child transmission, it is necessary to further increase the detection rate of antibodies in early pregnancy and the proportion of antiviral drugs used in infected women in early pregnancy.
【作者单位】：贺州市妇幼保健院;中国疾病预防控制中心妇幼保健中心;
【分类号】：R193;R512.91

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