厄尔尼诺-南方涛动现象与流行性感冒联系的系统评价

发布时间：2018-11-06 20:45

【摘要】：目的调查分析既往及正在执行的厄尔尼诺-南方涛动现象(El Ni1o-Southern Oscillation,ENSO)与流行性感冒关联的相关研究,并评价ENSO对流行性感冒相关指标(如流感流行高峰的出现时间、流感样病例报告人数等)的影响,为进一步开展天气及气象因素影响流感病毒传播研究提供依据和建议。方法计算机检索MEDLINE,EMBASE,Science Direct,HEED、中国生物医学文献数据库(CBMdisc)、万方学位论文全文数据库,查找1988~2016年10月已发表的关于ENSO与流行性感冒联系的文献,并运用循证医学方法进行文献数据提取和分析。结果共检索到78篇文献,其中符合纳入标准的已发表文献10篇。二次文献研究显示,出现ENSO与流感大流行的发生,流感高峰的出现时间,流感样病例就诊数及重症死亡数都有较大关联,且El Ni1o和La Ni1a现象对流感相关指标的影响也不尽相同。结论从纳入研究的已发表文献分析结果来看,ENSO与流行性感冒相关指标之间有较强的相关性。
[Abstract]:Objective To investigate the correlation between the previous and ongoing El Ni1o-Southern Oscillation (ENSO) and the influenza, and to evaluate the effect of ENSO on the related indexes of influenza (such as the occurrence time of the influenza epidemic peak, the number of cases of influenza-like cases, etc.). in ord to further develop that weather and meteorological factors, provide the basis and suggestion for the study of influenza virus transmission. Methods The paper searched MEDLINE, EMBASE, Science Direct, HEED, Chinese Biomedical Literature Database (CBMdisc), and the full-text database of Wanfang's degree thesis, and found the literature on the association between ENSO and influenza published in October, 2016. The method of evidence-based medicine was used to extract and analyze the literature data. Results A total of 78 articles were retrieved, including 10 published literature that met the inclusion criteria. The study of the secondary literature shows that the occurrence of ENSO and the influenza pandemic, the onset time of the peak of the influenza, the number of cases of flu-like cases and the number of severe deaths have been associated with each other, and the effects of El Ni1o and La Ni1a on the related indexes of the influenza are also different. Conclusion From the published literature analysis of the study, there is a strong correlation between ENSO and the related indexes of influenza.
【作者单位】：中国疾病预防控制中心病毒病预防控制所世界卫生组织全球流感参比和研究合作中心感染性疾病诊治协同创新中心卫生和计划生育委员会医学病毒和病毒病重点实验室;重庆医科大学公共卫生与管理学院;中国疾病预防控制中心;
【基金】：鄱阳湖地区人感染禽流感风险研究(美国NIH合作项目)资助~~
【分类号】：R511.7

【参考文献】