当前位置:主页 > 医学论文 > 传染病论文 >

2010-2015年浙江地区临床副溶血弧菌血清型分布及变迁分析

发布时间:2018-11-10 17:54
【摘要】:目的了解浙江地区2010-2015年临床副溶血弧菌血清型分布及变迁规律,为该菌流行病学调查及疫情暴发早期预警提供基础数据。方法收集浙江省8家医院急性腹泻患者来源的副溶血弧菌,采用玻片凝集法进行血清学分型,分析各年份血清型的构成及变迁情况。结果 2010-2015年共收集副溶血弧菌890株,其中864株(97.1%)发生O血清凝集,分为9个O群;以O3(507株,57.0%)为主,其次为O4(266株,30.0%)和O1(51株,5.7%)。650株(73.0%)发生K血清凝集,分属于23种K型,居首位的为K6(474株,53.3%)。发生凝集的菌株中共有43种O、K血清型组合,其中O3∶K6型是主要流行的血清型,共472株,占53.0%。2010-2015年中除2013年以O4∶KUT型为主,占56.2%(73/130);其他年份均以O3∶K6型为主,所占比例依次为:52.7%、68.5%、60.5%、50.3%和63.7%。连续6年均有出现的血清型有6种,分别为∶O3∶K6、O4∶KUT、O4∶K8、O4∶K68、O1∶K36和O1∶KUT型;且2013-2015年连续3年中血清型O1∶K36、O4∶K8和O4∶K68每年的构成比在0.5%~3.0%之间,与2010-2012年连续3年的3.0%~15.0%相比明显有所下降(P0.05)。结论浙江地区临床副溶血弧菌血清型分布较为广泛,以O3∶K6型为优势血清型。不同年份间存在一定的变异性。应加强对副溶血弧菌血清型的监测,为新血清型别的流行与暴发提供早期预警。
[Abstract]:Objective to investigate the distribution and changes of serotype of Vibrio parahaemolyticus from 2010 to 2015 in Zhejiang province, and to provide basic data for epidemiological investigation and early warning of outbreak of Vibrio parahaemolyticus. Methods Vibrio parahaemolyticus from acute diarrhea patients in 8 hospitals in Zhejiang Province were collected and serological typing was performed by slide agglutination method. The composition and changes of serotypes in each year were analyzed. Results A total of 890 strains of Vibrio parahaemolyticus were collected from 2010 to 2015, of which 864 (97.1%) developed O seroagglutination, which were divided into 9 O groups. O 3 (507 strains, 57.0%), O4 (266 strains, 30.0%) and O1 (51 strains, 5.7%). 650 strains (73.0%) showed K seroagglutination. 53.3%) There were 43 kinds of Oak serotype combinations, among which O3:K6 type was the most prevalent serotype, accounting for 472 strains, accounting for 53.0.2015.The predominant serotype was O4:KUT in 2013, accounting for 56.2% (73 / 130). In other years, O3:K6 type was the main type, and the proportion was 52.7%, 68.5% and 60.5%, 50.3% and 63.7%, respectively. There were 6 serotypes in 6 consecutive years. They were: O3: K6, O4: KUTO4: K8: O4: K68 / O1: K36 and O1:KUT; The ratio of serum O1: K36: O4: K8 and O4:K68 was between 0.5% and 3.0% in 2013-2015, which was significantly lower than that of 3.0% in 2010-2012 (P0.05). Conclusion the serotypes of Vibrio parahaemolyticus in Zhejiang province are widely distributed, with O3:K6 as the predominant serotype. There is certain variability between different years. The surveillance of serotype of Vibrio parahaemolyticus should be strengthened to provide early warning for the new serotype.
【作者单位】: 温州医科大学检验医学院生命科学学院;浙江大学医学院附属第一医院检验科浙江省临床体外诊断技术研究重点实验室;
【基金】:国家科技重大专项"传染病监测技术平台"项目(2012 ZX10004-210)
【分类号】:R446.5;R516

【相似文献】

相关期刊论文 前10条

1 万富明;欧丽琼;缪群英;;腹泻儿童感染致病性大肠埃希菌的血清型分布及耐药性[J];国际检验医学杂志;2013年13期

2 申阿东,朱荫芝,杨永弘,张桂荣,王咏红,江载芳;B组链球菌血清型分布和抗生素敏感性试验研究[J];中华围产医学杂志;2001年04期

3 任春阳;李向阳;杨锦红;周义正;;致病性大肠埃希菌血清型分布及对抗生素的敏感性分析[J];中国微生态学杂志;2007年04期

4 杨锦红;任春阳;王军;;肠致病性大肠埃希菌血清型分布及耐药性分析[J];实验与检验医学;2008年02期

5 吕素玲;韦程媛;姚雪婷;李秀桂;;2010年广西食品中沙门氏菌污染状况和血清型分布及耐药谱的研究[J];应用预防医学;2012年03期

6 董邦权;;临床分离的金黄色葡萄球菌产肠毒素血清型分布及意义[J];传染病信息;1994年02期

7 翁义星;李军;;福州地区人群Hp血清型分布调查[J];中国法医学杂志;1988年02期

8 陈秀英;38株致泻大肠艾希氏菌血清型分布及药敏检测[J];实用预防医学;2002年04期

9 吕素玲;韦程媛;李秀桂;;2011年广西沙门菌血清型分布及耐药分析[J];中国卫生检验杂志;2014年01期

10 姚开虎;俞桑洁;沈叙庄;佟月娟;高薇;杨永弘;;2000至2002年北京儿童中青霉素不敏感肺炎链球菌的血清型分布和同源性研究[J];中华微生物学和免疫学杂志;2007年10期



本文编号:2323175

资料下载
论文发表

本文链接:https://www.wllwen.com/yixuelunwen/chuanranbingxuelunwen/2323175.html


Copyright(c)文论论文网All Rights Reserved | 网站地图 |

版权申明:资料由用户818fa***提供,本站仅收录摘要或目录,作者需要删除请E-mail邮箱bigeng88@qq.com