Nd∶YAG 1064nm激光治疗甲真菌病的效果

发布时间：2018-12-29 10:46

【摘要】：目的观察Nd∶YAG 1 064 nm激光治疗甲真菌病的临床效果及安全性。方法 100例甲真菌病患者应用Nd∶YAG 1 064 nm激光治疗,每周1次,连续8周,参数:能量30~60 J/cm2,脉宽35 ms,光斑3 mm,根据患者年龄、临床类型、病甲位置、病甲受累程度分组比较疗效。结果 90例216个病甲完成治疗及随访,临床总有效率为81.9%。2~5指病甲及2~5趾病甲疗效优于拇指及拇趾病甲;白色浅表型、远端甲下型优于近端甲下型及全甲毁损型;30岁者及30~60岁者疗效均优于60岁者;甲受累面积30%者优于30%~60%者,后者疗效优于受累面积60%者;女性甲真菌病患者疗效好于男性,治疗过程中除疼痛外未发生其他不良反应。结论 Nd∶YAG 1 064 nm激光是治疗甲真菌病的一种安全有效的方法,疗效受到临床类型、病甲位置、发病年龄、甲受累面积及性别的影响。
[Abstract]:Objective to observe the clinical effect and safety of Nd:YAG 1 064 nm laser in the treatment of onychomycosis. Methods 100 patients with onychomycosis were treated with Nd:YAG 1 064 nm laser once a week for 8 weeks. The parameters were: energy 3060 J / cm 2, pulse width 35 ms, spot 3 mm, according to the age, clinical type and the location of the disease. The curative effect was compared among the groups of the degree of involvement of the diseased nail. Results the total effective rate of 90 cases with 216 nail diseases was 81.9%. The total effective rate was 81.9%, and the curative effect was better than that of thumb and hallux nail, white superficial type, distal subnail type was superior to proximal subnail type and total nail lesion type, and the total effective rate was 81.9%. The curative effect of 30 years old and 30 ~ 60 years old was better than that of 60 years old, and 30% of the cases with A involvement was better than 60% of the cases with 30% of the involved area, and the latter was better than the 60% of the cases with the affected area. The curative effect of female patients with onychomycosis was better than that of men. Conclusion Nd:YAG 1 064 nm laser is a safe and effective method for the treatment of onychomycosis.
【作者单位】：南昌大学第三附属医院皮肤医学美容科;
【基金】：南昌市指导性科技计划项目(编号:洪科发计字[2012]120号)
【分类号】：R756.4

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