中国医科大学附属第一医院就诊患者HIV抗体筛查试验结果分析

发布时间：2019-01-27 17:22

【摘要】：目的了解目前中国医科大学附属第一医院就诊患者中HIV感染发生情况,分析HIV感染者及HIV筛查试验呈假阳性反应者在各科室的分布情况及常见的实验室指标异常情况,探讨常规实验室指标对HIV初筛结果的影响。方法收集中国医大一院2012年5月至2013年3月就诊患者中HIV初筛阳性者的就诊信息,统计分析HIV感染阳性率,HIV感染者及HIV阴性患者的人群分布,及常规实验室指标与HIV初筛假阳性的相关性。结果就诊患者HIV初筛40 833人,确认实验阳性67人,阳性率为0.156%。在定性检测的实验室指标中,TP、GGT在HIV感染者的频率高于HIV初筛假阳性者(P=0.003 9,P=0.001 0),ALP、CA19-9在HIV初筛假阳性中频率有高于HIV感染者的趋势(P=0.0624,P=0.0969)。在定量检测的实验室指标量中,ASO GGT ALB AST有统计学意义,HIV初筛假阳性组中ALB的均值高于HIV感染者(P=0.022)。结论 ALP、CA19-9、ALB实验室检测结果的异常可能与HIV初筛假阳性相关。
[Abstract]:Objective to investigate the prevalence of HIV infection among the patients in the first affiliated Hospital of China Medical University, and to analyze the distribution of HIV infection and false positive HIV screening test in different departments and the abnormal laboratory indexes. To investigate the effect of routine laboratory indexes on the results of HIV screening. Methods from May 2012 to March 2013, the information of patients with HIV positive screening was collected, and the positive rate of HIV infection and the distribution of HIV infected patients and HIV negative patients were analyzed statistically. And the correlation between routine laboratory indexes and false positive of HIV screening. Results 40 833 patients were screened for HIV, 67 of them were positive in the experiment, the positive rate was 0.156. The frequency of TP,GGT in HIV infected patients was higher than that in HIV false positive individuals (P0. 0039 / P0. 001 0), and the frequency of ALP,CA19-9 in HIV was higher than that in HIV infected persons (P0. 0624). P0. 0969). There was statistical significance in the quantity of, ASO GGT ALB AST in the laboratory index of quantitative detection. The average value of ALB in the false positive group of HIV screening was higher than that in the infected group of HIV (P0. 022). Conclusion the abnormal results of ALP,CA19-9,ALB laboratory may be related to false positive of HIV screening.
【作者单位】：铁岭卫生职业学院;
【分类号】：R512.91

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