泰州市实施全球基金耐多药结核病防治项目两年效果分析

发布时间：2019-02-14 17:54

【摘要】：目的分析我市实施全球基金耐多药结核病防治项目工作效果,为今后制定耐多药结核病控制策略提供依据。方法对2012年4月至2014年6月期间,我市全球基金结核病项目报表、实验室登记本、耐多药肺结核病案等资料进行分析。结果全球基金项目期间,我市共筛查耐多药可疑者1 081例,筛查率86.07%,耐多药肺结核检出率6.30%,广泛耐多药检出率0.25%,新患者耐多药检出率显著低于其他不同类别的涂阳病人的检出率(χ2=81.69,P0.01)。确诊52例耐多药病人,患者纳入治疗率78.85%,治疗6个月时,痰涂片阴转率66.67%,痰培养阴转率63.33%。治疗满12个月时,痰涂片及培养阴转率均为54.17%。结论通过全球基金项目的实施,我市建立了"地级市诊疗,县区级筛查,社区督导服药"的耐多药结核病防治新模式,耐多药防治工作得到加强和提高,为今后防治工作提供了良好的指导和借鉴。
[Abstract]:Objective to analyze the effect of global fund multi-drug resistance TB control project in our city, and to provide basis for formulating control strategy of MDR-TB in the future. Methods from April 2012 to June 2014, the data of TB project report, laboratory register and multi-drug resistant pulmonary tuberculosis (MDR-TB) were analyzed. Results during the period of the Global Fund Project, 1 081 cases of suspicious multidrug resistance were screened in our city, the screening rate was 86.07, the detection rate of multidrug resistance tuberculosis was 6.30, and the detection rate of extensive multidrug resistance was 0.25%. The detection rate of multidrug resistance in new patients was significantly lower than that in other smear positive patients (蠂 2 / 81.69 / P0.01). 52 patients with multidrug resistance were diagnosed, and the rate of treatment was 78.85. After 6 months of treatment, the sputum smear negative conversion rate was 66.67 and the sputum culture negative conversion rate was 63.33. After 12 months of treatment, the sputum smear and culture negative rate were 54.17%. Conclusion through the implementation of the Global Fund project, we have established a new model of multi-drug resistant tuberculosis prevention and treatment, which is called "prefectural level, county level screening, community supervision taking medicine", and the prevention and treatment of multi-drug resistance has been strengthened and improved. It provides good guidance and reference for the prevention and cure work in the future.
【作者单位】：江苏省泰州市疾病预防控制中心;
【分类号】：R52

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