儿童应用抗结核药物引起肝毒性反应的相关因素分析

发布时间：2019-02-25 08:54

【摘要】：目的分析儿童应用抗结核药物引起肝毒性反应的相关因素,以探究儿童针对抗结核药物的应用方案。方法将我院于2014年7月~2015年7月期间收入实施门诊或住院治疗的64例结核病患儿作为观察对象,并将其分为观察组和对照组,各32例。观察组患儿均为用药后出现肝毒性反应,对照组患儿均为用药后无不良反应出现。结果经对研究对象留存资料进行分析可知,其患儿应用抗结核药物后发生肝毒性反应主要由年龄过小、体质不佳、用药方案等因素所引起。结论儿童在应用抗结核药物时极有可能会由于年龄、体质、用药方案等多种因素引起肝毒性反应,因此需在其认知基础上做相应的用药方案调整,以便为相关疾病患儿提供更为优质的医疗质量。
[Abstract]:Objective to analyze the related factors of hepatotoxicity induced by antituberculotic drugs in children, and to explore the application of antituberculotic drugs in children. Methods from July 2014 to July 2015, 64 children with tuberculosis received outpatient or inpatient treatment in our hospital as observation objects, and were divided into observation group and control group, 32 cases in each group. All the children in the observation group showed hepatotoxicity after medication, while the control group showed no adverse reactions. Results based on the analysis of the retention data of the subjects, the hepatotoxicity of children with antituberculotic drugs was mainly caused by the factors such as too young age, poor constitution, medication scheme and so on. Conclusion it is very possible for children to cause hepatotoxic reactions due to age, physique, medication regimen and other factors when using antituberculotic drugs. Therefore, it is necessary to adjust the medication scheme on the basis of their cognition. In order to provide a better quality of medical care for children with related diseases.
【作者单位】： 南阳市第六人民医院西药房;
【分类号】：R529.9

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