乙肝五项指标两种检测方法的应用价值

发布时间：2019-03-29 12:19

【摘要】：目的了解不同检测方法对乙肝五项指标的临床检测结果的影响以及应用价值。方法选取本院2015-2016年期间收治乙肝患者相关临床资料纳入本文研究对象内,抽取1500份标本并分别接受化学发光酶免疫法(CLEIA)以及酶联免疫吸附试验法(ELISA)对患者乙肝五项相关指标进行检测,通过回顾性分析后归纳两种临床常用乙肝五项指标检测手段数据的阳性率以及符合率。结果对所有标本经过两种方法检测后,提示血清当中乙肝五项在阳性率方面数据差异经统计学软件处理提示并无明显差异(P0.05)。结论临床检测乙肝五项指标方法中CLEIA以及ELISA两种手段均有着令人满意的敏感性和特异性,其中ELISA检测手段具有操作方便、结果快捷的优点,可在基层医院广泛推广,但出现假阳性、假阴性情况概率较高,CLEIA检测方法有突出的敏感性和特异性,同时在定量方面也有突出价值,相比之下更有利于医生掌握患者体内乙肝病毒的具体状况,值得临床重视推广。
[Abstract]:Objective to investigate the effect of different detection methods on the clinical results of five indexes of hepatitis B and its application value. Methods the clinical data of hepatitis B patients treated in our hospital from 2015 to 2016 were selected and included in this study. 1500 samples were collected and detected by chemiluminescent enzyme immunoassay (CLEIA) and enzyme linked immunosorbent assay (ELISA). After retrospective analysis, the positive rate and coincidence rate of two kinds of clinical data of five indexes of hepatitis B were summarized. Results the results showed that there was no significant difference in the positive rate of the five items of hepatitis B in serum between the two methods (P0.05). Conclusion both CLEIA and ELISA have satisfactory sensitivity and specificity in clinical detection of hepatitis B, and ELISA detection has the advantages of convenient operation and quick results, which can be widely used in basic hospitals. But false positive, false negative situation probability is higher, CLEIA detection method has outstanding sensitivity and specificity, at the same time also has outstanding value in quantitative aspect, by contrast, it is more conducive to doctors to grasp the specific situation of hepatitis B virus in patients' body. Clinical attention should be attached to the promotion.
【作者单位】：吉林省白山市长白朝鲜族自治县医院检验科;
【分类号】：R446.6;R512.62

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