广西地区艾滋病患者认知功能初步调查

发布时间：2019-04-20 07:45

【摘要】：目的了解广西地区艾滋病患者的认知功能。方法选择广西南宁市第四人民医院根据实验室确诊的艾滋病患者80例作为病例组;同时从陪同家属中选取近3个月内无可感染艾滋病病毒的危险行为,艾滋病病毒抗体检测阴性88例作为对照组,应用蒙特利尔认知评估量表(MoCA)的中文翻译版,对两组对象进行认知功能调查及评估。结果病例组总分为2~29分,平均(20.04±6.13)分,其中认知功能损害48例(60.00%);对照组总分为17~29分,平均(25.02±2.98)分,其中认知功能损害6例(6.82%)。病例组MoCA量表总分、视觉与执行力、命名、延迟回忆、注意力、抽象能力及定向力项得分均低于对照组(P0.01)。两组对象在各得分段人员分布及比例方面比较,差异有统计学意义(P0.05)。对性别、年龄、文化程度3个因素进行了Logistic回归分析,只有文化程度是影响因素。结论艾滋病患者中存在不同程度的认知功能损害,文化程度可能是影响该量表得分的因素。
[Abstract]:Objective to investigate the cognitive function of AIDS patients in Guangxi. Methods 80 cases of AIDS confirmed by laboratory in the fourth people's Hospital of Nanning, Guangxi were selected as the case group. At the same time, 88 HIV antibody negative cases were used as control group, and the Chinese translation version of Montreal Cognitive Assessment scale (MoCA) was used to evaluate the risk behavior of no HIV infection in the accompanying families in the last 3 months. The cognitive function of the two groups was investigated and evaluated. Results the total score of the patients group was (20.04 卤6.13), including 48 cases of cognitive impairment (60.00%), and the total score of the control group was 17% (25.02 卤2.98), of which 6 cases (6.82%) had cognitive impairment. The total score, visual and executive power, naming, delayed recall, attention, abstraction and orientation of the MoCA scale in the case group were lower than those in the control group (P0.01). The difference was statistically significant between the two groups in the distribution and proportion of each segment (P0.05). Logistic regression analysis was carried out on the three factors of gender, age and educational level, and only the educational level was the influencing factor. Conclusion there are different degrees of cognitive impairment in AIDS patients, and the degree of education may be the factor influencing the score of the scale.
【作者单位】：广西壮族自治区柳州市柳城县疾病预防控制中心公共卫生管理科;广西医科大学第一附属医院神经内科;广西医科大学公共卫生学院;
【基金】：广西艾滋病防治重点实验室开放课题(gxlabpt201304)
【分类号】：R512.91

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