安徽省局部地区人群隐孢子虫感染情况调查

发布时间：2019-05-08 13:30

【摘要】：目的了解安徽省人群隐孢子虫感染状况,探讨感染的危险因素,为隐孢子虫病防治提供科学依据。方法选择安徽省潜山县和灵璧县为调查点,于2014年9月-2015年1月,采用改良抗酸染色法和酶联免疫吸附试验(ELISA)法,分别检查调查对象粪便中隐孢子虫卵囊和血清中隐孢子虫特异性抗体Ig G,以确定隐孢子虫感染情况;同时对调查对象进行问卷调查,了解隐孢子虫感染的危险因素。结果共调查668人,其中病原学检查635人,阳性15人,阳性率为2.36%;血清学检查642人,阳性140人,阳性率为21.81%;有628人同时进行了病原学和血清学检查,两种检查方法均为阳性者12人(潜山县4人,灵璧县8人),阳性率为1.94%。潜山县与灵璧县人群隐孢子虫感染率分别为1.24%(4/322)和2.71%(8/295),差异无统计学意义(P0.05)。单因素χ2分析发现,隐孢子虫感染率在儿童及腹泻人群较高;多因素Logistics回归分析表明,隐孢子虫感染率在饲养家禽人群及腹泻人群较高。结论安徽省局部地区人群隐孢子虫血清抗体阳性率较高,提示既往感染较为严重。人群隐孢子虫感染率与低龄、腹泻和家庭饲养家禽有关,在今后防治工作中值得关注。
[Abstract]:Objective to investigate the infection status of Cryptosporidium in Anhui Province and to explore the risk factors for the prevention and treatment of cryptosporidiosis. Methods from September 2014 to January 2015, modified acid-fast staining method and enzyme-linked immunosorbent assay (ELISA) were used in Qianshan County and Lingbi County of Anhui Province. The specific antibody Ig-G of Cryptosporidium oocysts in feces and serum of the investigated subjects were examined to determine the infection of Cryptosporidium. At the same time, a questionnaire survey was conducted to understand the risk factors of Cryptosporidium infection. Results A total of 668 cases were investigated, including 635 cases of etiological examination, 15 cases of positive rate (2.36%), 642 cases of serological examination, 140 cases of positive rate (21.81%). Both etiological and serological tests were carried out in 628 people. 12 of them were positive (4 in Qianshan County and 8 in Lingbi County), the positive rate was 1.94%. The infection rates of Cryptosporidium in Qianshan County and Lingbi County were 1.24% (4 鈮，

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