四川省2010-2014年新报告的HIV感染者中新发感染情况分析

发布时间：2019-05-17 18:42

【摘要】：目的了解四川省近年新报告1型艾滋病病毒(HIV-1)感染病例中,新发感染病例的流行特征及相关影响因素。方法收集2010-2014年各年第一季度,在四川省所有确证实验室检测确证为阳性的新报告病例的血清样本和相关信息,用BED发病捕获酶联免疫法(BED-CEIA)对血清样本进行检测,并根据社会人口学特征对新报告HIV病例及BED阳性病例分组并计算构成比,分析相关影响因素。结果 2010-2014年各年第一季度,四川省新报告病例9445例,新发感染病例(BED阳性)2222人,阳性率为23.53%。各年分别为1702、1403、1761、2011和2568例,BED阳性率分别为22.80%(388人)、23.88%(335人)、22.71%(400人)、22.53%(453人)和25.20%(646人)。各年新报告病例均主要为男性,汉族和彝族为主,教育程度为初中或以下为主。近年来,50岁人群新报告病例比例呈现上升趋势,传播途径从2010年的注射毒品(48.11%)和性传播(46.83%)并行,到2014年以性传播为主(73.64%)。多因素Logistic回归分析显示,年龄(20岁年龄组)、民族(彝族)和传播途径(男男性行为)均是新发感染的影响因素。结论四川省青年、老年人群、彝族以及男男性行为人群中,HIV感染状况十分严峻,且存在快速传播危险,应加大防控力度。
[Abstract]:Objective to investigate the epidemic characteristics and related influencing factors of newly reported HIV-1 1 infection cases in Sichuan Province in recent years. Methods the serum samples and related information of newly reported cases confirmed to be positive in all confirmed laboratories in Sichuan Province were collected in the first quarter of 2010-2014, and the serum samples were detected by BED capture enzyme-linked immunosorbent assay (BED-CEIA). According to the characteristics of social demography, the newly reported HIV cases and BED positive cases were divided into two groups and the constituent ratio was calculated, and the related influencing factors were analyzed. Results in the first quarter of 2010-2014, 9445 newly reported cases and 2222 new infections (BED positive) were reported in Sichuan Province, the positive rate was 23.53%. The positive rates of BED were 22.80% (388), 23.88% (335), 22.71% (400), 22.53% (453) and 25.20% (646), respectively. In each year, the new reported cases were mainly male, Han and Yi, and the education level was mainly junior high school or below. In recent years, the proportion of newly reported cases among 50-year-old people has shown an upward trend, from injecting drugs (48.11%) to sexual transmission (46.83%) in 2010 and sexual transmission (73.64%) in 2014. Multivariate Logistic regression analysis showed that age (20 years old group), nationality (Yi nationality) and transmission route (male and male sex) were all the influencing factors of new infection. Conclusion among the young, elderly, Yi and male sex people in Sichuan Province, the situation of HIV infection is very serious, and there is a risk of rapid transmission, so we should strengthen the prevention and control.
【作者单位】：四川省疾病预防控制中心;四川省凉山州疾病预防控制中心;
【分类号】：R512.91

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