2010年福建省肠道病毒71型血清流行病学调查

发布时间：2019-06-01 19:33

【摘要】：目的了解经过2008及2009年手足口病流行之后,福建省普通人群血清肠道病毒71型的抗体水平。方法采集2010年福建省390名普通人群的血清标本,采用中和试验检测血清EV71中和抗体。结果 390名普通人群中和抗体阳性186人,阳性率47.69%。男女性别之间中和抗体阳性率及抗体滴度均没有统计学差异(χ2=0.42,P=0.520.05;U=-0.24,P=0.810.05)。各个年龄组之间的抗体阳性率及抗体滴度均有统计学差异(χ2=55.69,P=0.000.05;HC=50.36,P=0.000.05),抗体阳性率最低的为0~岁年龄组,为16.67%,抗体阳性率随年龄增大而增高。0~4岁年龄组的抗体阳性率为25.33%,5~年龄组的抗体阳性率为61.67%,两者之间的抗体阳性率及抗体滴度均有统计学差异(χ2=48.85,P=0.000.05;U=-6.39,P=0.000.05)。结论经过2008及2009年手足口病流行之后,福建省普通人群血清肠道病毒71型的抗体水平仍较低,特别是0~4岁年龄组的儿童。今后福建省仍会出现EV71作为主要病原体之一引起的手足口病疫情,易感人群仍为5岁组以下儿童,应继续加强监测和防控。
[Abstract]:Objective to investigate the antibody level of serum enterovirus 71 in Fujian province after the epidemic of HFMD in 2008 and 2009. Methods the serum samples of 390 general population in Fujian Province in 2010 were collected and the neutralizing antibody of serum EV71 was detected by neutralization test. Results 186 of 390 general population were positive for neutralizing antibody, the positive rate was 47.69%. There was no significant difference in neutralizing antibody positive rate and antibody titer between male and female (蠂 2 = 0.42, P 鈮，

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