G试验在深部真菌感染快速诊断中的临床价值探讨

发布时间：2019-06-15 03:44

【摘要】：目的通过分析血浆(1,3)-β-D葡聚糖(G试验)、真菌培养结果与真菌感染的相关性,探讨G试验在深部真菌感染(DFI)快速诊断中的临床价值。方法选择2013年9月-2016年1月,861例疑诊为DFI的患者进行G试验及真菌培养,分析G试验与真菌培养对DFI的诊断效率。结果在疑诊为DFI 861例患者中,临床诊断为DFI组181例,非DFI组680例。G试验与真菌培养阳性率分别为29.27%(252/861)和21.37%(184/861),两者比较,差异有统计学意义(P0.05)。G试验诊断DFI的敏感性、特异性、阳性预测值、阴性预测值及准确度分别为89.50%、86.76%、64.29%、96.88%和87.34%;真菌培养诊断DFI的敏感性、特异性、阳性预测值、阴性预测值及准确度分别为59.12%、88.68%、58.15%、89.07%和82.46%。结论 G试验在快速、早期诊断DFI中有重要临床价值。
[Abstract]:Objective to analyze the correlation between plasma (1, 3)-尾-D dextran (G test), fungal culture results and fungal infection, and to explore the clinical value of G test in the rapid diagnosis of deep fungal infection (DFI). Methods from September 2013 to January 2016, 861 patients suspected of DFI were selected for G test and fungal culture, and the diagnostic efficiency of G test and fungal culture for DFI was analyzed. Results the positive rates of G test and fungal culture were 29.27% (252 鈮，

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