早期小剂量普瑞巴林预防老年带状疱疹后遗神经痛的临床观察
发布时间：2019-07-26 16:33
【摘要】：目的探讨早期小剂量普瑞巴林预防老年带状疱疹后遗神经痛的临床效果。方法选择近一年时间内在我院住院治疗的老年带状疱疹患者共计100例,按随机原则将100例患者分成观察组和对照组,每组50例患者。两组患者均给予静滴更昔洛韦针,口服甲钴胺片,联合红光治疗;观察组患者在此基础上给予口服小剂量普瑞巴林进行治疗。结果两组患者治疗前的VAS评分比较,P0.05差异不具有统计学意义;两组患者治疗后的VAS评分比较差异显著,其中观察组患者的VAS评分显著较低,P0.05差异具有统计学意义。观察组患者后遗神经痛发生率为0,对照组患者后遗神经痛发生率为10.0%(5/50),P0.05差异具有统计学意义。观察组患者嗜睡1例、头晕2例,不良反应发生率为6.0%,对照组患者上腹部不适2例,不良反应发生率4.0%,P0.05差异不具有统计学意义。结论早期应用小剂量普瑞巴林可快速缓解老年带状疱疹患者急性期的疼痛症状,对于降低患者后遗神经痛发生率,改善患者生活质量具有显著的作用,且具有较好的临床安全性和耐受性。
[Abstract]:Objective to investigate the clinical effect of early low dose prednisone in the prevention of postherpetic neuropain in the elderly. Methods A total of 100 elderly patients with herpes zoster who were hospitalized in our hospital in recent one year were randomly divided into observation group (n = 50) and control group (n = 50). Both groups were treated with ganciclovir intravenous injection, oral mecobalamin tablets combined with red light, while the patients in the observation group were treated with oral low dose prednisolone. Results there was no significant difference in VAS score between the two groups before treatment, and there was no significant difference in VAS score between the two groups after treatment, and the VAS score of the observation group was significantly lower than that of the observation group, and the difference between the two groups was statistically significant. The incidence of sequelae neuralgia in the observation group was 0, while that in the control group was 10.0% (5 鈮，
本文编号：2519664
[Abstract]:Objective to investigate the clinical effect of early low dose prednisone in the prevention of postherpetic neuropain in the elderly. Methods A total of 100 elderly patients with herpes zoster who were hospitalized in our hospital in recent one year were randomly divided into observation group (n = 50) and control group (n = 50). Both groups were treated with ganciclovir intravenous injection, oral mecobalamin tablets combined with red light, while the patients in the observation group were treated with oral low dose prednisolone. Results there was no significant difference in VAS score between the two groups before treatment, and there was no significant difference in VAS score between the two groups after treatment, and the VAS score of the observation group was significantly lower than that of the observation group, and the difference between the two groups was statistically significant. The incidence of sequelae neuralgia in the observation group was 0, while that in the control group was 10.0% (5 鈮，
本文编号：2519664
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