慢性HBV/HCV感染人群伴随的免疫相关表现
发布时间:2021-11-06 19:42
慢性HBV/HCV感染者常常伴有自身免疫系统紊乱,在丙型肝炎中尤为常见。介绍了慢性丙型肝炎患者免疫状态紊乱的机制,出现非器官特异性自身抗体的比例,以及伴随的免疫相关疾病,如混合型冷球蛋白血症、肾小球肾炎、干燥综合征、甲状腺疾病、2型糖尿病的临床表现、诊断和治疗等。简述了慢性乙型肝炎患者免疫状态紊乱的机制、相关的免疫表现以及抗病毒治疗对其的影响。慢性乙型或丙型肝炎的抗病毒治疗可以减轻伴随的免疫系统疾病,但是不宜采用干扰素治疗,因此,乙型肝炎患者应采用核苷和核苷酸类药物治疗,丙型肝炎患者应采用直接抗病毒药物治疗。
【文章来源】:临床肝胆病杂志. 2016,32(10)
【文章页数】:4 页
【文章目录】:
1 慢性HCV感染免疫状态紊乱
1.1 慢性HCV感染中的自身抗体
1.2 慢性HCV感染中的免疫相关疾病
1.2.1 混合型冷球蛋白血症
1.2.2 肾小球肾炎
1.2.3 干燥综合征
1.2.4 甲状腺疾病
1.2.5 2型糖尿病
2 慢性HBV感染免疫状态紊乱
3 小结
【参考文献】:
期刊论文
[1]Direct acting antiviral therapy is curative for chronic hepatitis C/autoimmune hepatitis overlap syndrome[J]. Farhad Sahebjam,Cristina H Hajdu,Esther Nortey,Samuel H Sigal. World Journal of Hepatology. 2016(14)
[2]Hepatitis C virus and neurological damage[J]. Shilu Mathew,Muhammed Faheem,Sara M Ibrahim,Waqas Iqbal,Bisma Rauff,Kaneez Fatima,Ishtiaq Qadri. World Journal of Hepatology. 2016(12)
[3]Anti-rods/rings autoantibody generation in hepatitis C patients during interferon-α/ribavirin therapy[J]. Gerson Dierley Keppeke,S John Calise,Edward KL Chan,Luis Eduardo C Andrade. World Journal of Gastroenterology. 2016(06)
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本文编号:3480413
【文章来源】:临床肝胆病杂志. 2016,32(10)
【文章页数】:4 页
【文章目录】:
1 慢性HCV感染免疫状态紊乱
1.1 慢性HCV感染中的自身抗体
1.2 慢性HCV感染中的免疫相关疾病
1.2.1 混合型冷球蛋白血症
1.2.2 肾小球肾炎
1.2.3 干燥综合征
1.2.4 甲状腺疾病
1.2.5 2型糖尿病
2 慢性HBV感染免疫状态紊乱
3 小结
【参考文献】:
期刊论文
[1]Direct acting antiviral therapy is curative for chronic hepatitis C/autoimmune hepatitis overlap syndrome[J]. Farhad Sahebjam,Cristina H Hajdu,Esther Nortey,Samuel H Sigal. World Journal of Hepatology. 2016(14)
[2]Hepatitis C virus and neurological damage[J]. Shilu Mathew,Muhammed Faheem,Sara M Ibrahim,Waqas Iqbal,Bisma Rauff,Kaneez Fatima,Ishtiaq Qadri. World Journal of Hepatology. 2016(12)
[3]Anti-rods/rings autoantibody generation in hepatitis C patients during interferon-α/ribavirin therapy[J]. Gerson Dierley Keppeke,S John Calise,Edward KL Chan,Luis Eduardo C Andrade. World Journal of Gastroenterology. 2016(06)
[4]Autoantibodies in chronic hepatitis C: A clinical perspective[J]. Janaína Luz Narciso-Schiavon,Leonardo de Lucca Schiavon. World Journal of Hepatology. 2015(08)
[5]Extrahepatic immune related manifestations in chronic hepatitis C virus infection[J]. Maria Tampaki,John Koskinas. World Journal of Gastroenterology. 2014(35)
[6]Useful biomarkers for assessment of hepatitis C virus infection-associated autoimmune disorders[J]. Deng-Ho Yang,Ling-Jun Ho,Jenn-Haung Lai. World Journal of Gastroenterology. 2014(11)
[7]慢性丙型肝炎患者血清自身抗体检测的研究[J]. 吴赤红,徐小元,田庚善,于岩岩. 中华医学杂志. 2006(06)
本文编号:3480413
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