Sustained release of isoniazid from polylactide microspheres

发布时间：2021-11-11 15:46

　　Polylactide（PLA） microspheres were prepared using the solid-in-oil（S/O） spray-drying method to achieve the sustained release of a hydrophilic drug for the treatment of tuberculosis, via intratracheal instillation. Isoniazid（IN）, a low-molecular-weight hydrophilic drug, was used as a model drug. The effects of various sizes of micronized IN powder, different drug/polymer ratios, spray-drying process parameters, and drug-release characteristics were studied to optimize the manufacturing parameters... 

【文章来源】：Science China（Life Sciences）. 2016,59(07)SCICSCD

【文章页数】：8 页

【部分图文】：

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图.曰口』目石m仓(h1


本文编号：3489125