家兔大型艾美尔球虫四川株的致病性和免疫原性研究

发布时间：2018-03-07 00:35

  本文选题：兔　切入点：大型艾美尔球虫　出处：《西南农业学报》2017年05期 　论文类型：期刊论文

【摘要】：【目的】为调查兔大型艾美尔球虫四川株的致病性和免疫原性。【方法】本研究利用实验室分离到的大型艾美尔球虫四川株进行了动物感染试验。【结果】5×10~3和5×10~4个卵囊组的SPF兔在接种后第4~9天,出现轻微的食欲减少症状;5×10~5组在接种后第6~8天持续中度腹泻,第8天体重与对照组有明显差异(P≤0.05),但均无死亡现象。感染剂量为5×10~3时卵囊产量最多,为2.31×10~8;免疫原性实验中,7×10~5个卵囊攻毒后,5×10~3卵囊免疫组卵囊排出最少,为6.28×10~4,各组体重与对照组相比无明显差异。【结论】大型艾美尔球虫四川株致病性较弱,但免疫原性良好,可作为兔球虫疫苗的备选组分。
[Abstract]:[objective] to investigate the pathogenicity and immunogenicity of Sichuan strain of large Eimeria rabbit. [methods] the animal infection test was carried out by using Sichuan strain isolated from laboratory. [results] 5 脳 10 ~ 3 and 5 脳 10 ~ 4 eggs were obtained. The SPF rabbits in the capsule group were inoculated on the 4th and 9th day after inoculation. Moderate diarrhea continued on the 6th day after inoculation in the 5 脳 10 ~ (5) group with mild appetite loss symptoms. There was a significant difference in body weight between the control group and the control group on the 8th day (P 鈮，

本文编号：1577217