仔猪肠道微生物研究进展

发布时间：2018-11-22 08:52

【摘要】：肠道菌群在哺乳动物及人类健康的作用正日益受到重视。仔猪的健康生长需要一个动态平衡的肠道微生态环境。然而,在猪的生命周期中,从食管到直肠的微生物分布与组成存在时间和空间的变化。健康的肠道菌群具有促进猪的营养代谢,维持肠黏膜屏障,调节免疫应答,抑制病原菌感染等功能。多种因素对猪肠道菌群的形成与稳定具有重要的作用,包括分娩方式(经过产道或剖宫产)、幼龄时期饮食(母乳或配方饲料)、抗生素或抗生素样分子的使用等。本文主要从仔猪肠道微生物组成与定植、功能、影响肠道微生物的因素等方面论述了仔猪肠道微生物与仔猪肠道健康的关系,从而加深肠道微生物对维护仔猪肠道健康作用的认识。
[Abstract]:The role of intestinal flora in mammalian and human health is receiving increasing attention. The healthy growth of piglets requires a dynamic and balanced intestinal microecological environment. However, the distribution and composition of microbes from esophagus to rectum vary in time and space during the life cycle of pigs. Healthy intestinal flora has the functions of promoting nutrition metabolism, maintaining intestinal mucosal barrier, regulating immune response and inhibiting pathogen infection. A variety of factors play an important role in the formation and stability of intestinal flora in pigs, including delivery mode (via birth canal or cesarean section), infant diet (breast milk or formula feed), use of antibiotics or antibiotic like molecules, etc. In this paper, the relationship between intestinal microorganism and intestinal health of piglets was discussed from the following aspects: composition and colonization, function of intestinal microorganism and factors affecting intestinal microorganism. So as to deepen the understanding of intestinal microbes to maintain the intestinal health of piglets.
【作者单位】：中国科学院亚热带农业生态研究所畜禽健康养殖研究中心中国科学院亚热带农业生态过程重点实验室畜禽养殖污染控制与资源化技术国家工程实验室湖南省畜禽健康养殖工程技术研究中心农业部中南动物营养与饲料科学观测实验站;中国科学院大学;第三军医大学基础部实验动物学教研室;
【基金】：国家自然科学基金(No.31330075,No.31301989)
【分类号】：S828

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