2013—2016年四川省猪繁殖与呼吸综合征病继发细菌感染的病原学分析

发布时间：2019-01-07 16:53

【摘要】：为给近几年临床控制和治疗PRRSV继发感染提供参考依据,对2013—2016年来自四川省各地感染PRRSV的112头病猪病料进行细菌分离,经形态学观察、选择培养、生化鉴定。分离得到葡萄球菌(MRS)、链球菌、多杀性巴氏杆菌(PM)、大肠埃希菌(Escherichia coli)、猪胸膜肺炎放线杆菌(App)。其中葡萄球菌的分离率最高(70%),其次为多杀性巴氏杆菌(50%),大肠埃希菌(40%),猪胸膜肺炎放线杆菌(40%),链球菌(30%);继发感染主要发生于肝脏和肺脏,其次是脾和心包积液。动物试验结果表明,多杀性巴氏杆菌、大肠埃希菌、链球菌、胸膜肺炎放线杆菌具有致病性。药敏试验结果表明:多杀性巴氏杆菌对环丙沙星敏感,对庆大霉素中度敏感;大肠埃希菌对丁胺卡那敏感,对氨苄西林、庆大霉素、新霉素中度敏感;链球菌对卡那霉素中度敏感;猪胸膜肺炎放线菌对环丙沙星中度敏感。
[Abstract]:In order to provide reference for clinical control and treatment of secondary infection of PRRSV in recent years, 112 infected pigs infected with PRRSV from different parts of Sichuan Province were isolated from 2013 to 2016. Staphylococcus (MRS), Streptococcus, Pasteurella multocida (PM), Escherichia coli (Escherichia coli), Actinobacillus pleuropneumoniae (App). The isolation rate of Staphylococcus was the highest (70%), followed by Pasteurella multocida (50%), Escherichia coli (40%), Actinobacillus pleuropneumoniae (40%) and Streptococcus (30%). Secondary infection mainly occurred in liver and lung, followed by spleen and pericardial effusion. Animal tests showed that Pasteurella multocida, Escherichia coli, streptococcus, actinobacillus pleuropneumoniae had pathogenicity. The results of drug sensitivity test showed that Pasteurella multocida was sensitive to ciprofloxacin and moderately sensitive to gentamicin, Escherichia coli to amikacin, ampicillin, gentamicin and neomycin. Streptococcus was moderately sensitive to kanamycin and Actinomyces pleuropneumoniae was moderately sensitive to ciprofloxacin.
【作者单位】：四川农业大学动物医学院;四川农业大学四川省动物疫病与人类健康重点实验室;
【基金】：国家“十二五”科技支撑计划(2015BAD12B04-2.3) 四川省科技支撑计划(2014NZ0043)
【分类号】：S858.28

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