不同水平玉米赤霉烯酮对断奶母仔猪血清酶、代谢产物和肠道形态的影响

发布时间：2019-02-17 17:46

【摘要】：本试验旨在研究不同水平玉米赤霉烯酮(ZEA)对断奶母仔猪血清酶、代谢产物和肠道形态的影响。选取28日龄平均体重为(14.01±0.86)kg、健康的三元杂交(杜×长×大)雌性断奶仔猪40头,随机分为4组,每组10头。对照组饲喂基础饲粮,试验1组、试验2组和试验3组在基础饲粮中分别添加0.5、1.0和1.5 mg/kg ZEA。预试期10 d,正试期35 d。结果表明:1)与对照组相比,各试验组的谷草转氨酶、碱性磷酸酶和乳酸脱氢酶活性显著升高(P0.05);试验2组的血清总胆固醇含量显著升高(P0.05);试验3组血清尿素氮和高密度脂蛋白(HDL)含量显著升高(P0.05),血清总蛋白含量则显著降低(P0.05)。2)与对照组相比,试验组十二指肠和空肠绒毛高度和隐窝深度都显著增大(P0.05)。试验1组和试验2组十二指肠绒毛高度/隐窝深度值显著提高(P0.05),空肠绒毛高度/隐窝深度值显著降低(P0.05),回肠绒毛高度和绒毛高度/隐窝深度值都显著升高(P0.05)。3)与对照组相比,试验组十二指肠绒毛高度明显增大且排列疏松无序,小肠腺数量减少,黏膜厚度变薄。4)与对照组相比,试验组空肠绒毛高度增大,小肠腺数量减少,并且试验2组和试验3组空肠上皮脱落固有层裸露。5)与对照组相比,试验1组和试验2组回肠绒毛高度增大且黏膜下层内弥散淋巴细胞增多。由此可见,饲粮中添加ZEA(0.5~1.5 mg/kg)改变了断奶母仔猪的肝脏代谢和肠道的形态结构,进而影响断奶母仔猪的健康生长。
[Abstract]:The purpose of this study was to study the effects of different levels of zearalenone (ZEA) on serum enzymes, metabolites and intestinal morphology in weaned piglets. Forty female weaned piglets with average body weight of (14.01 卤0.86) kg, were randomly divided into 4 groups, 10 in each group. The control group was fed with basic diet, the experimental group 1, the experimental group 2 and the experimental group 3 were supplemented with 0. 5 mg/kg ZEA. and 1. 5 mg/kg ZEA. in the basal diet, respectively. The pre-test period was 10 days and the current test period was 35 days. The results showed that: 1) compared with the control group, the activities of glutamic oxaloacetic transaminase, alkaline phosphatase and lactate dehydrogenase in each trial group were significantly increased (P0.05), and the serum total cholesterol content in test group 2 was significantly higher than that in control group (P0.05). The levels of serum urea nitrogen and high density lipoprotein (HDL) were significantly increased (P0.05), and the serum total protein contents were significantly decreased (P0.05) in the trial 3 groups compared with the control group. The villi height and crypt depth of duodenum and jejunum were significantly increased in the experimental group (P0.05). The value of duodenal villus height / crypt depth increased significantly (P0.05), and the jejunal villus height / crypt depth value decreased significantly (P0.05) in group 1 and group 2, respectively. Compared with the control group, the villi height and villi height / crypt depth in the experimental group were significantly increased and loosely arranged, and the number of small intestinal glands decreased, compared with the control group. Compared with the control group, the jejunal villus height increased and the number of small intestinal glands decreased in the experimental group, and the exfoliated lamina propria of the jejunum epithelium was exposed in the treatment group 2 and 3) compared with the control group. In group 1 and group 2, the villus height of ileum increased and the number of diffuse lymphocytes in submucous layer increased. Thus, the addition of ZEA (0.5 ~ 1.5 mg/kg) in diet changed the liver metabolism and intestinal morphology of weaned piglets, and then affected the healthy growth of weaning piglets.
【作者单位】：山东农业大学动物科技学院;生百兴业有限公司;
【基金】：山东省现代农业产业技术体系生猪创新团队专项资金(SDAIT-08-05) 国家自然科学基金资助项目(31572441) “双一流”奖补资金资助
【分类号】：S859.8

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