儿童癫痫共患孤独症

发布时间：2018-01-26 11:56

本文关键词： 癫痫孤独症共患病儿童　出处：《中国实用儿科杂志》2017年04期 　论文类型：期刊论文

【摘要】：癫痫和孤独症共患是较为常见的临床现象,5%~37%的癫痫儿童共患孤独症(或孤独症筛查阳性),2%~46%的孤独症或孤独症谱系障碍患者共患癫痫。精神疾病家族史、围生期不利因素、女性、孤独症特征、智力障碍、遗传或神经综合征、遗传因素等增加两种疾病共患风险。两种疾病共患时,癫痫起病更早,存在学龄前和青春期两个起病高峰,部分性发作更多见,难治性发生率更高,孤独症症状更严重,智力障碍更突出,运动发育问题和行为症状更多见,适应不良更明显。及时识别、正确诊断和规范治疗两种疾病非常重要。
[Abstract]:Epilepsy and autism comorbidity is a clinical common phenomenon, 5%~37% in children with epilepsy with autism (autism or screening), comorbid patients with autism or autism spectrum disorder epilepsy 2%~46%. Family history of mental disorders, perioperative adverse factors, female students, autistic traits, mental disorders, genetic or neurological syndrome, genetic factors such as increased two kinds of disease comorbidity risk. Two kinds of diseases that, earlier onset epilepsy, there are two preschool and adolescent onset peak, partial seizures are more common and intractable higher incidence, more serious symptoms of autism, mental retardation is more prominent, motor development problems and behavior symptoms are more common, maladjustment is more obvious. Timely recognition, correct diagnosis and standardized treatment of two diseases is very important.

【作者单位】：北京大学精神卫生研究所北京大学第六医院卫生部精神卫生学重点实验室国家精神心理疾病临床医学研究中心(北京大学);
【分类号】：R742.1;R749.94
【正文快照】： 癫痫是儿童期较为常见的一种神经系统疾病,以大脑神经元异常放电引起短暂中枢神经系统功能失常为特征。孤独症是一种起病于婴幼儿时期的神经发育障碍,以社会交往障碍、交流障碍、兴趣与行为狭窄、刻板与重复为主要临床表现。两种疾病临床表现不同,但是症状和诊断在同一个个体

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