晚期早产儿振幅脑电图变化特点及影响因素分析

发布时间：2018-02-03 00:14

本文关键词： 脑电描记术婴儿早产婴儿新生疾病婴儿小于胎龄窒息　出处：《福建医科大学学报》2017年03期 　论文类型：期刊论文

【摘要】：目的探讨晚期早产儿生后早期振幅整合脑电图(aEEG)变化特点,并分析影响aEEG的临床因素。方法分析65例晚期早产儿aEEG变化。探讨胎龄、宫内营养、窒息和临床严重疾病等因素对aEEG影响。采用χ~2检验、非参数检验及Logistic回归分析进行统计学分析。结果 (1)胎龄越长,晚期早产儿aEEG评分越高(χ~2=13.6,P=0.01);(2)窒息严重程度越重,aEEG异常发生率越高(χ~2=15.3,P=0.02);(3)合并临床严重疾病组aEEG异常发生率高(χ~2=11.6,P=0.01);(4)Logistic回归分析提示,合并临床严重疾病是aEEG结果异常的独立危险因素(OR=1.2,95%CI:1.1~10.7,P=0.04);(5)除临床严重疾病因素外,窒息也是aEEG结果异常独立危险因子(OR=1.5,95%CI:1.5~15.1,P=0.01);(6)aEEG成熟度评分与NBNA评分正相关(r=0.77,P=0.02)。结论随着胎龄增长,晚期早产儿aEEG逐渐成熟,但窒息和临床严重疾病等因素是影响aEEG的独立危险因素,临床上应关注合并高危因素的晚期早产儿脑功能变化。
[Abstract]:Objective to investigate the changes of amplitude integrated electroencephalogram (aEEG) in the early postnatal stage of advanced preterm infants, and to analyze the clinical factors affecting aEEG. Methods 65 cases of late premature infants were analyzed for the changes of aEEG and the gestational age. The effects of intrauterine nutrition, asphyxia and severe clinical diseases on aEEG were analyzed by 蠂 ~ 2 test, non-parametric test and Logistic regression analysis. The aEEG score of advanced preterm infants was higher (蠂 2 13.6% P < 0.01). (2) the more severe the degree of asphyxia, the higher the incidence of abnormal AEEG (蠂 2 15. 3% P0. 02); (3) the incidence of abnormal aEEG in the patients with severe clinical diseases was high (蠂 2 + 11.6% P < 0.01). Logistic regression analysis showed that severe clinical diseases were the independent risk factors for abnormal outcome of aEEG. P0. 04; (5) asphyxia was also an independent risk factor for abnormal aEEG results. There was a positive correlation between the maturity score of NBNA and the maturity score of NBNA. Conclusion with the increase of gestational age, aEEG of late premature infants matures gradually. However, asphyxia and severe clinical diseases are independent risk factors for aEEG. Therefore, attention should be paid to the changes of brain function of late premature infants with high risk factors.
【作者单位】：福建医科大学附属第一医院新生儿科;
【基金】：福建省卫生和计划生育委员会青年科研课题(2014-1-51)
【分类号】：R722.6;R741.044
【正文快照】： (2017)03-0190-05晚期早产儿以往称为近足月儿,指胎龄34~36+6周的早产儿,约占早产儿的70%[1]。研究表明,晚期早产儿出生人数逐年增加,其住院期间低血糖、黄疸、呼吸暂停、呼吸窘迫综合征及神经发育障碍的发生率等均明显高于足月儿[2-3]。近年来,晚期早产儿的呼吸系统、感染、

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