儿童不同程度心肌致密化不全临床特点分析

发布时间：2018-02-12 09:27

本文关键词： 心肌致密化不全临床特征转归儿童　出处：《临床儿科杂志》2017年10期 　论文类型：期刊论文

【摘要】：目的探讨不同程度心肌致密化不全患儿的临床特征及预后,探讨非致密化心肌层与致密心肌层厚度之比(N/C)的临床指导意义。方法回顾分析心肌致密化不全患儿的临床资料,比较N/C2.0和N/C 1.4~2.0两组患儿的情况。结果两组患儿各26例,年龄、性别、低出生体质量和营养不良比例,心脏病变及合并症的差异均无统计学意义(P0.05)。出院时N/C2.0组病情好转8例,无明显好转15例,死亡3例;N/C 1.4~2.0组病情好转18例,无明显好转8例,无死亡病例。两组治疗有效率差异有统计学意义(χ2=7.69,P=0.006)。随访出院后8年内N/C2.0组病死率高于N/C 1.4~2.0组,差异有统计学意义(χ~2=6.993,P=0.008)。结论心肌致密化不全患儿的N/C值越大,治疗有效率越低,预后越差。
[Abstract]:Objective to investigate the clinical characteristics and prognosis of children with different degree of myocardial compaction insufficiency, and to explore the clinical significance of the ratio of nondensified myocardial layer to compact myocardial layer thickness. Methods the clinical data of children with myocardial densification insufficiency were retrospectively analyzed. Results there were 26 cases of age, sex, low birth weight and malnutrition ratio, no significant difference in heart disease and complications between the two groups (P 0.05). There were no obvious improvement in 15 cases, 3 cases died in group N / C 1.42.0, 18 cases improved, 8 cases did not improve, and there was no death case. There was a significant difference between the two groups in the effective rate of treatment (蠂 2 / 7.69 / P 0.006). The fatality rate of group N / C 2.0 was higher than that of group N / C 1.42.0 within 8 years after discharge from hospital. Conclusion the greater the N- / C value of the children with myocardial compaction, the lower the effective rate and the worse the prognosis.
【作者单位】：重庆医科大学附属儿童医院心内科儿童发育疾病研究教育部重点实验室儿童发育重大疾病国家国际科技合作基地儿科学重庆市重点实验室;
【基金】：国家自然科学基金面上项目(No.81270234、81570218) 重庆市科委民生项目(No.cstc2016shmszx130003)
【分类号】：R725.4

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