舒芬太尼在儿童全麻肠镜检查中的临床应用

发布时间：2018-03-15 03:01

本文选题：舒芬太尼　切入点：芬太尼　出处：《中国内镜杂志》2017年05期 　论文类型：期刊论文

【摘要】：目的观察舒芬太尼在儿童全麻肠镜检查中的临床效果和安全性。方法择期全麻下行肠镜检查患儿80例,年龄5~10岁,体重18~35 kg,随机分为舒芬太尼组(S组)和芬太尼组(F组),每组40例。S组静注舒芬太尼0.2μg/kg,F组静注芬太尼2.0μg/kg,随后两组均静注丙泊酚2.50 mg/kg,置入双腔喉罩,丙泊酚6.00~8.00 mg/(kg·h)泵注复合七氟醚2%~3%维持麻醉。记录麻醉诱导前(T_0)、放置喉罩时(T_1)、肠镜至回盲瓣时(T_2)及手术结束时(T_3)等时点的心率(HR)、平均动脉压(MAP)、脉搏氧饱和度(Sp O_2)及呼吸频率(RR),同时记录苏醒时间、注射部位疼痛、术中体动、术中有无返流、术后舌后坠、恶心呕吐、咽喉部疼痛及躁动等情况。结果 F组在T1和T2时HR、MAP高于麻醉诱导前(P0.05),而S组HR、MAP差异无统计学意义(P0.05)。T_1时两组RR均较诱导前明显降低(P0.05),组间比较差异无统计学意义(P0.05)。T_1、T_2时S组HR和MAP明显低于F组(P0.05)。S组注射疼、诱导及苏醒时间、术后躁动发生率均较F组低(P0.05)。结论舒芬太尼用于静吸复合全麻双腔喉罩通气下行小儿肠镜检查安全有效,麻醉效果满意,术中呼吸循环更稳定,术后苏醒质量高。
[Abstract]:Objective to observe the clinical effect and safety of sufentanil in children with general anesthesia. The rats were randomly divided into sufentanil group (n = 40) and fentanyl group (n = 40) and fentanyl group (n = 40). Sufentanil 0.2 渭 g / kg / kg F group was given fentanyl 2.0 渭 g / kg, and then propofol 2.50 mg / kg / kg was injected intravenously. Propofol 6. 00 mg/(kg 路h) pump combined with sevoflurane 2% maintenance anaesthesia. Record the heart rate HRR, mean arterial pressure (MAPP), pulse oxygen saturation (SPO 2), pulse oxygen saturation (SPO 2), pulse oxygen saturation (SPO 2) at the time points such as T 0, T 1, T 2) when the laryngeal mask is placed, and T 2 at the end of the operation and at the end of the operation. At the same time, the time of awakening was recorded. Injection site pain, intraoperative body movement, intraoperative reflux, postoperative tongue drop, nausea and vomiting, Results HRMAP at T1 and T2 in group F was higher than that before anesthesia induction, but there was no significant difference in HRMAP between group S and group S (P 0.05). The RR of group T 1 was significantly lower than that of group B (P 0.05), but there was no significant difference between the two groups. HR and MAP in group S were significantly lower than those in group F (P 0.05). The incidence of postoperative restlessness in group F was lower than that in group F. ConclusionSufentanil is safe and effective in the examination of pediatric colonoscopy under double lumen laryngeal mask ventilation with intravenous inhalation and general anesthesia, and the effect of anesthesia is satisfactory, and the respiration and circulation are more stable during operation. The quality of postoperative recovery is high.
【作者单位】：南京医科大学附属儿童医院麻醉科;
【分类号】：R726.1

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