运用五运六气浅析武汉地区2001年-2010年儿童肺炎支原体感染率差异

发布时间：2018-03-21 01:48

本文选题：五运六气　切入点：肺炎支原体感染　出处：《湖北中医药大学》2012年硕士论文　论文类型：学位论文

【摘要】：目的：本课题旨在研究武汉地区2001年～2010年的气候特点及儿童肺炎支原体高发年份和高发季节,并通过中医五运六气理论推算出2001年～2010年武汉地区的气候特点及流行疾病的高发年份,从而探讨两者之间的相关性。方法：收集武汉地区2001年1月～2010年12月因呼吸道感染在武汉市协和医院、武汉市同济医院、湖北省妇幼保健院、武汉市第一医院儿科和武汉市儿童医院就诊的患儿102547例,其中男63237例,女39310例,年龄最小1个月,最大14岁。采集患者静脉血,分离血清,采用ELISA方法(酶联免疫吸附试验)检测患者血清中的特异性MP-IgM抗体,操作严格按照试剂说明进行。对不同年份,不同季度的MP-IgM抗体的阳性率进行统计。实验结果分析采用SPSS13.0统计软件,分类资料用x2检验,计量资料用t检验,等级资料用Ridit检验。并收集2001年1月～2010年12月武汉地区每月气象资料,来自湖北省气象局。结果：1.该实验结果显示2001、2002、2003、2004、2005、2006、2007、2008、2009、2010年的阳性率分别为6.72%、16.52%、25.93%、21.63%、16.63%、14.98%、22.71%、15.79%、12.23%、16.12%。其中以2003年最高为25.93%,2001年最低为6.72%。2003的阳性率显著高于2001年(x2=130.505,P0.01)。2001年～2010年的第一季度、第二季度、第三季度和第四季度的阳性率分别为17.72%、9.63%、12.87%和23.18%。第四季度的阳性率显著高于第一季度、第二季度和第三季度(χ2分别为210.995、1796.083、925.830,P0.01)。2.通过五运六气理论推演武汉地区的气候特点与武汉地区实际气候特点相符率不高,但其推算流行疾病的高发年份与武汉地区儿童肺炎支原体的高发年份一致,推算肺系疾病的高发季节与武汉地区儿童肺炎支原体的高发季节一致。结论：通过中医五运六气理论推演武汉地区的气候特点存在一定的可行性,推算武汉地区儿童肺炎支原体感染的高发年份、高发季节具有一定的准确性。
[Abstract]:Objective: to study the climatic characteristics and the year and season of high incidence of mycoplasma pneumoniae in Wuhan from 2001 to 2010. The climatic characteristics and the year of high prevalence of epidemic diseases in Wuhan from 2001 to 2010 were calculated by the theory of "five Transport and six Qi" in traditional Chinese Medicine, and the correlation between them was discussed. Methods: from January 2001 to December 2010, 102547 cases of children with respiratory tract infection were collected from Xianhe Hospital of Wuhan City, Tongji Hospital of Wuhan City, Maternal and Child Health Hospital of Hubei Province, Pediatrics Department of the first Hospital of Wuhan City and Children's Hospital of Wuhan City. Among them, 63237 males and 39310 females, aged from 1 month to 14 years, collected venous blood, isolated serum and detected the specific MP-IgM antibody in the serum of patients by ELISA assay (enzyme-linked immunosorbent assay), and the specific MP-IgM antibody in the serum of the patients was determined by enzyme-linked immunosorbent assay (Elisa). The operation was carried out strictly according to the reagent instructions. The positive rate of MP-IgM antibody in different years and different quarters was counted. The SPSS13.0 statistical software was used to analyze the experimental results, the classification data was tested by x2, and the measurement data was tested by t test. The grade data were checked by Ridit and collected monthly meteorological data from January 2001 to December 2010 in Wuhan from Hubei Meteorological Bureau. Results 1. The results of this experiment show that the positive rates of 2001 / 2002 / 2003 / 2005 / 2007 / 2008 / 2009, respectively, on 2010 were 6.722 / 16.522 and 25.932 / 21.63A, respectively. The positive rates were significantly higher in the first quarter from 2001 to 2001, and in the second quarter of 2001, when the highest was 25.933 in 2003, and the lowest in 2001 was 6.722.05, P 0.01.The highest was 25.93in 2003 and the lowest 6.725.2003 in 2001. The positive rates in the third quarter and 4th quarter were 17.72% and 23.18%, respectively. The positive rates were significantly higher in the third quarter than in the first quarter. In the second quarter and the third quarter (蠂 ~ 2 = 210.995 / 1796.083 / 925.830 / P0.01 / 2 respectively), the climatic characteristics of Wuhan region were deduced by the theory of "five transport and six gases", and the coincidence rate between the climatic characteristics and the actual climatic characteristics in Wuhan was not high. But the year of high incidence of epidemic disease was consistent with that of childhood mycoplasma pneumoniae in Wuhan area, and the high incidence season of pulmonary diseases was consistent with that of children with mycoplasma pneumoniae in Wuhan area. Conclusion: it is feasible to extrapolate the climatic characteristics of Wuhan area by the theory of "five Transport and six Qi" in traditional Chinese Medicine. The high incidence year of mycoplasma pneumoniae infection in children in Wuhan area is calculated, and the high incidence season has certain accuracy.
【学位授予单位】：湖北中医药大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R725.6

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