肺炎支原体感染对婴幼儿喘息发作的影响研究

发布时间：2018-04-23 23:28

本文选题：肺炎支原体 + 感染　；参考：《中华医院感染学杂志》2017年13期

【摘要】：目的探究感染肺炎支原体对婴幼儿喘息发作的影响,为预防婴幼儿喘息发作提供科学依据。方法选取2014年3月-2016年6月医院治疗的196例被不同病原菌感染的婴幼儿作为研究对象,其中包括铜绿假单胞菌感染组婴幼儿41例、肺炎克雷伯菌感染组婴幼儿39例、肺炎支原体感染组婴幼儿84例和金黄色葡萄球菌感染组婴幼儿32例;比较不同病原体感染组患者喘息类型构成,检测四组婴幼儿总免疫球蛋白E含量与嗜酸性粒细胞计数并进行比较。结果支原体组一次性喘息患儿31例占36.9%,铜绿假单胞菌感染一次性喘息患儿11例占26.8%,肺炎克雷伯菌感染一次性喘息患儿9例占23.1%,金黄色葡萄球菌感染组一次性喘息患儿8例占25%;支原体组多次性喘息患儿38例占45.2%,铜绿假单胞菌感染多次性喘息患儿15例占36.6%,肺炎克雷伯菌感染多次性喘息患儿12例占30.8%,金黄色葡萄球菌感染组多次性喘息患儿13例占40.6%;支原体组无喘息患儿15例占17.8%,铜绿假单胞菌感染无喘息患儿15例占36.6%,肺炎克雷伯菌感染无喘息患儿18例占46.2%,金黄色葡萄球菌感染组无喘息患儿11例占34.4%,不同病原菌感染组比较差异有统计学意义(P0.05)。结论婴幼儿感染肺炎支原体能够对婴幼儿喘息发作产生促进作用,当婴幼儿肺炎支原体感染时,喘息发作的可能性明显增加。
[Abstract]:Objective to investigate the effect of mycoplasma pneumoniae infection on infant wheezing attack and provide scientific basis for prevention of infant wheezing attack. Methods 196 infants with different pathogens were selected from March 2014 to June 2016, including 41 infants infected with Pseudomonas aeruginosa and 39 infants infected with Klebsiella pneumoniae. 84 infants in mycoplasma pneumoniae infection group and 32 infants in staphylococcus aureus infection group. Total immunoglobulin E content and eosinophil count were measured and compared among the four groups. Results in mycoplasma group, there were 31 children with one-time wheezing, 11 children with pseudomonas aeruginosa infection, 9 children with Klebsiella pneumoniae infection with one-time wheezing, and those with Staphylococcus aureus infection. In mycoplasma group, 38 cases (45.2%) had multiple wheezing, 15 cases (36.6%) with Pseudomonas aeruginosa infection, 12 cases (30.8%) with Klebsiella pneumoniae infection, and more cases with Staphylococcus aureus infection. 13 cases of secondary asthmatic children (40.6%), 15 cases of mycoplasma group without wheezing children (17.8%), 15 cases of Pseudomonas aeruginosa infection (36.6 cases), 18 cases of Klebsiella pneumoniae infection (46.2%) and staphylococcus aureus infection group (46.2%). There were 11 cases (34. 4%) in children with different pathogenic bacteria infection group, the difference was statistically significant (P 0. 05). Conclusion Mycoplasma pneumoniae infection can promote infant wheezing attack, and when infantile mycoplasma pneumoniae infection, the possibility of wheezing attack is obviously increased.
【作者单位】：华中科技大学同济医学院附属武汉儿童医院(武汉市妇幼保健院)重症医学科;华中科技大学同济医学院附属武汉儿童医院(武汉市妇幼保健院)风湿免疫科;南京鼓楼医院心血管内科;
【基金】：武汉市卫生局公共卫生科研基金资助项目(WG12B01)
【分类号】：R725.6

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