母亲出生体重与新生儿出生体重的关系研究

发布时间：2018-05-01 19:38

本文选题：婴儿 + 小于胎龄　；参考：《中华疾病控制杂志》2017年03期

【摘要】：目的探讨母亲出生体重与新生儿出生体重的关系,以便为研究母亲宫内发育不良对子代发育的影响提供线索。方法通过巢式病例对照研究,采用多重线性回归分析了解母亲出生体重与新生儿出生体重的关系,并以非条件Logistic回归分析进一步探讨母亲出生体重对小于胎龄儿(small for gestational age,SGA)、大于胎龄儿(large for gestational age,LGA)的影响。结果 SGA的发生率为7.04%,LGA发生率为14.65%。多重线性回归分析结果显示,母亲出生体重与新生儿出生体重呈正相关,母亲出生体重每增加1 kg,新生儿出生体重增加174 g(β=0.174,95%CI:0.134~0.213)。随母亲出生体重的增加,SGA发生率递减(χ_(趋势)~2=13.791,P0.001),LGA的发生率递增(χ_(趋势)~2=7.900,P=0.005),母亲低出生体重(2 500 g)是SGA的危险因素(OR=2.458,95%CI:1.333~4.534);以孕期增重分层分析后,结论一致,但出生体重较低的孕妇(2 500 g)孕期增重不足会导致SGA发生风险增高。结论孕妇出生体重低是分娩SGA的危险因素,随着孕妇出生体重增加,新生儿出生体重增大,但未发现LGA与孕妇出生体重有关。
[Abstract]:Objective to explore the relationship between mother's birth weight and newborn's birth weight in order to provide clues for studying the influence of mother's intrauterine dysplasia on offspring development. Methods A nested case-control study was conducted to study the relationship between mother's birth weight and newborn's birth weight by multiple linear regression analysis. The effect of mother's birth weight on small for gestational (SGAA) and large for gestational (LGA) of small for gestational were further studied by non conditional Logistic regression analysis. Results the incidence of SGA was 7.04% and 14.65%. Multiple linear regression analysis showed that the birth weight of the mother was positively correlated with the birth weight of the newborn. Every 1 kg increase in the birth weight of the mother increased the birth weight of the newborn by 174 g (尾 0.174% 95% CI: 0.134% 0.213%). With the increase of birth weight of mother, the incidence of SGA decreased (蠂 _ 2: 213.791n / P 0.001p _ (0.001) (蠂 ~ + / T _ (27.900) is a risk factor of SGA (2.45895CIW 1.33334.534g). But low birth weight pregnant women with 2 500 g) gain less weight during pregnancy can lead to a higher risk of SGA. Conclusion low birth weight of pregnant women is a risk factor of SGA. With the increase of birth weight of pregnant women, newborn weight increases, but LGA is not found to be related to birth weight of pregnant women.
【作者单位】：山西医科大学公共卫生学院流行病学教研室;耶鲁大学公共卫生学院环境健康科学系;山西医科大学第一医院妇产科;
【基金】：国家自然科学基金(81473061) 山西省青年科技研究基金(2013021033-2) 山西省普通高校特色重点学科建设项目(2012年) 山西医科大学十人计划项目(2015年)
【分类号】：R722.6

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