婴幼儿喘息的相关因素分析

发布时间：2018-05-30 01:41

本文选题：婴幼儿 + 喘息　；参考：《宁夏医学杂志》2015年02期

【摘要】：目的分析婴幼儿喘息与其血清总Ig E、肺功能及社会因素的关系,为临床早期诊治提供理论依据。方法收集住院患儿(28 d年龄≤3岁)共300例,其中喘息性疾病(包括毛细支气管炎、喘息性支气管炎、婴幼儿哮喘)患儿150例为病例组,同期住院的下呼吸道感染而无喘息症状患儿150例为对照组,检测其血清总Ig E值、行肺功能检查,比较2组其差异性;并对入选患儿行流调问卷调查,从中分析引起婴幼儿喘息的相关因素。结果病例组中喘息性支气管炎、婴幼儿哮喘患儿的血清总Ig E水平明显高于对照组患儿,TEF 25%、TEF 50%、TPTEF/Te、VPTEF/Ve均明显低于对照组;病例组患儿喘息与反复呼吸道感染病史、个人过敏疾病史、家族哮喘或过敏病史、既往使用抗生素、被动吸烟、家中养花草有关。结论婴幼儿喘息时其血清总Ig E水平明显升高,肺功能水平明显下降;婴幼儿喘息的相关因素为反复呼吸道感染病史、个人过敏疾病史、家族哮喘或过敏病史、既往使用抗生素、被动吸烟、家中养花草。
[Abstract]:Objective to analyze the relationship between infant wheezing and serum IgE, pulmonary function and social factors so as to provide theoretical basis for early clinical diagnosis and treatment. Methods A total of 300 hospitalized children aged less than 3 years (28 days old) were collected. 150 cases of asthmatic diseases (including bronchiolitis, wheezing bronchitis and infantile asthma) were selected as the case group. 150 children with lower respiratory tract infection and no wheezing symptoms in the same period were taken as control group. The serum IgE value and pulmonary function were measured, and the difference between the two groups was compared. The related factors of infant wheezing were analyzed. Results the serum levels of IgE in asthmatic bronchitis and asthmatic infants were significantly higher than those in the control group, and the levels of TEF25 and TEF50 were significantly lower than those in the control group, and the history of wheezing and recurrent respiratory tract infection and individual allergic diseases were significantly lower in the case group than in the control group. Family history of asthma or allergies, previous use of antibiotics, passive smoking, home gardening. Conclusion the levels of serum IgE and pulmonary function in infants with wheezing were significantly increased, and the related factors of infant wheezing were history of recurrent respiratory tract infection, history of individual allergic disease, family history of asthma or allergic disease. Previous use of antibiotics, passive smoking, home gardening.
【作者单位】：宁夏医科大学;宁夏医科大学总医院儿科;
【基金】：宁夏自然科学基金资助项目(NZ1217)
【分类号】：R725.6

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