自拟“平喘汤”治疗外寒内热型儿童哮喘的临床观察

发布时间：2018-06-05 22:23

本文选题：自拟“平喘汤” + 儿童支气管哮喘急性发作期(外寒内热型)　；参考：《广州中医药大学》2012年硕士论文

【摘要】：目的：运用前瞻性的临床研究方法,观察自拟“平喘汤”治疗外寒内热型儿童支气管哮喘的临床疗效,同时进行呼气峰流速(PEF)的测定,初步探讨PEF的变化与该证型症候积分的相关性。方法：随机收集符合研究标准的外寒内热型支气管哮喘急性发作期的患儿共60例,其中治疗组与对照组各30例。对照组采用常规治疗,治疗组用常规治疗加用自拟“平喘汤”,治疗5天后,观察两组治疗前后中医症候积分和PEF的变化。运用SPSS17.0及Excel统计软件分析观察结果。成果： 1.综合疗效：治疗组：显效率86.67%；对照组：显效率56.67%,(P0.05),治疗组显效率优于对照组。 2.中医症候积分：治疗前后经统计学检验两者差异具有统计学意义(P0.01)。并且治疗后治疗组与对照组之间的差异有统计学意义(P0.05)。两组的治疗均可以减少中医症候积分,治疗组优于对照组。 3.治疗前后PEF变化：两组的PEF均较治疗前有所提高,两组提高的幅度经统计学检验,两者之间的差异有统计学意义(P0.05),治疗组在改善PEF方面优于对照组。 4.应急雾化吸入次数：两组哮喘急性发作期的治疗均有应急雾化吸入,但是治疗组的雾化吸入次数少于对照组(P0.05)。 5.中医症候的改善与PEF的变化有一定的相关性。结论： 1.自拟“平喘汤”联合西医常规治疗能明显改善外寒内热型儿童支气管哮喘的中医症候积分,提高显效率且在改善咳嗽、咳痰、喘息症状及肺部哮鸣音等主症上优于对照组。 2.治疗前后治疗组与对照组均可以提高PEF,改善气道痉挛,缓解症状,但治疗组优于对照组。 3.中西医结合治疗可以减少雾化吸入次数。 4.外寒内热型儿童支气管哮喘的中医症候变化与PEF的变化有一定的相关性。
[Abstract]:Objective: To observe the clinical effect of "Pingchuan decoction" in the treatment of bronchial asthma in children with external cold and internal heat, and to determine the peak expiratory flow rate (PEF), and to explore the correlation between the change of PEF and the symptom score of the syndrome. Methods: A total of 60 children with acute attack of external cold and internal heat asthma were randomly collected, including 30 cases in the treatment group and 30 cases in the control group. The control group was treated with routine therapy, the treatment group was treated with conventional therapy and the self-made "Pingchuan decoction" was used. After 5 days of treatment, the changes of TCM symptom score and PEF were observed before and after treatment. SPSS17.0 and Excel software were used to analyze the observation results. Outcome: 1. Comprehensive efficacy: the treatment group: the effective rate was 86.67; the control group: the effective rate was 56.67 and P0.05. The effective rate of the treatment group was better than that of the control group. 2. TCM symptom score: before and after treatment, the difference between the two was statistically significant (P 0.01). The difference between the treatment group and the control group was statistically significant (P 0.05). Both groups of treatment can reduce TCM symptom score, the treatment group is better than the control group. 3. The changes of PEF before and after treatment: the PEF of the two groups were improved compared with those before treatment, and the amplitude of the two groups was increased by statistical test. The difference between the two groups was statistically significant (P 0.05). The treatment group was superior to the control group in improving PEF. 4. The times of emergency atomization inhalation: both groups had emergency atomization inhalation during the acute attack of asthma, but the times of atomization inhalation in the treatment group were less than that in the control group (P 0.05). 5. The improvement of TCM symptoms is related to the change of PEF. Conclusion: 1. The self-made "Pingchuan decoction" combined with western medicine routine treatment can obviously improve the TCM symptom integral of children's bronchial asthma with external cold and internal heat type, and improve the effective rate and is superior to the control group in improving the main symptoms such as cough, expectoration, wheezing symptoms and lung wheezing. 2. Before and after treatment, both the treatment group and the control group could improve PEF, improve airway spasm and relieve symptoms, but the treatment group was superior to the control group. 3. Integrated Chinese and Western medicine treatment can reduce the number of atomization inhalation. 4. The changes of TCM symptoms and changes of PEF in children with external cold and internal heat type bronchial asthma are related to some extent.
【学位授予单位】：广州中医药大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R272

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