儿童眶周毛母质瘤46例临床及病理分析

发布时间：2018-06-28 12:19

本文选题：毛母质瘤 + 钙化上皮瘤　；参考：《眼科新进展》2017年10期

【摘要】：目的分析儿童眶周毛母质瘤的临床及病理特点。方法对2012年2月至2017年2月入住我院的46例确诊为眶周毛母质瘤并行手术的儿童患者的临床、病理资料进行回顾性研究。结果 46例患儿中男18例、女28例(男∶女=1.00∶1.56)。发病部位眉弓26例(56.5%)、上睑18例(39.1%)、下睑2例(4.3%)。病理学检查瘤体在光镜下可见主要由两种细胞组成:基底细胞样细胞和影细胞。46例肿瘤中36例间质内有钙化灶,25例有炎性细胞浸润,24例可见多核巨细胞。所有病例经手术切除,术后无一例复发或恶变。结论毛母质瘤具有典型的临床特征和病理特征,发病部位在眶周的儿童患者并不少见,熟练掌握其临床特征及眶周常见肿物的鉴别诊断将有助于提高诊断准确率。
[Abstract]:Objective to analyze the clinical and pathological features of orbital hair mother tumor in children. Methods the clinical and pathological data of 46 children with orbital hair mother tumor admitted to our hospital from February 2012 to February 2017 were retrospectively studied. Results there were 18 males and 28 females in 46 cases (male: 1.00: 1.56). There were 26 cases (56.5%) with eyebrow arch, 18 cases (39.1%) with upper eyelid and 2 cases (4.3%) with lower eyelid. Pathological examination showed that the tumor was mainly composed of two kinds of cells under light microscope: basal cell-like cells and shadow cells. In 36 cases, calcification foci were found in the interstitium of 25 cases, inflammatory cells infiltrated in 24 cases and multinucleated giant cells were found in 24 cases. All cases were resected and no recurrence or malignant change occurred after operation. Conclusion Dermatogonoma has typical clinical and pathological features, and it is not uncommon in children with periorbital lesions. Mastering its clinical features and differential diagnosis of common orbital masses will help to improve the accuracy of diagnosis.
【作者单位】：南京医科大学附属儿童医院眼科;
【基金】：国家自然科学基金资助(编号:81400406)~~
【分类号】：R739.7

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