早产与足月新生儿坏死性小肠结肠炎临床对比分析

发布时间：2018-07-09 11:38

  本文选题：早产儿 + 足月儿　； 参考：《重庆医科大学学报》2017年08期

【摘要】：目的:对比分析早产与足月新生儿坏死性小肠结肠炎(neonatal necrotizing enterocolitis,NEC)的临床特点。方法:回顾性分析338例NEC临床资料,比较患儿围产期相关信息、NEC诊断后并发症、治疗情况及预后危险因素。结果:早产组94例,足月组244例,早产组胎膜早破发生率高于足月组;早产组NEC诊断后并发败血症、呼吸衰竭高于足月组;早产组NEC诊断后多巴胺、IVIG使用率及输注红细胞高于足月组(均P0.05)。logistic回归分析发现,影响早产组预后不良的危险因素为Ⅲ期NEC(OR=6.725,95%CI=2.153~21.01,P=0.001)及并发败血症(OR=3.78,95%CI=1.204~11.873,P=0.023);足月组为Ⅲ期NEC(OR=7.762,95%CI=3.392~15.23,P=0.000)。结论:NEC在早产、足月儿人群发病的围产期因素、并发症、预后危险因素方面存在差异,早产儿并发症更多。Ⅲ期NEC是导致患儿预后不良的共同危险因素,并发败血症是导致早产患儿预后不良的额外危险因素。
[Abstract]:Objective: to compare the clinical features of (neonatal necrotizing enterocolitis (NEC) between preterm and term neonates with necrotizing enterocolitis. Methods: the clinical data of 338 cases of NEC were analyzed retrospectively. The related information of perinatal period and complications, treatment and prognostic risk factors of NEC were compared. Results: the incidence of premature rupture of membranes in premature delivery group was higher than that in term group, 94 cases in premature delivery group and 244 cases in term group, the incidence of premature rupture of membranes was higher in preterm group than in term group, and the incidence of septicemia and respiratory failure in preterm group was higher than that in term group. Logistic regression analysis showed that the risk factors influencing the prognosis of preterm labor group were stage 鈪，

本文编号：2109236