小儿腹部手术后应用生长抑素的疗效观察

发布时间：2018-08-03 15:40

【摘要】：目的评估生长抑素应用于小儿腹部手术后的临床疗效和安全性。方法该研究共纳入2014年1月-2016年6月在海南省人民医院行腹部手术的急腹症患儿120例,将其随机分为观察组(60例)和对照组(60例)。腹部手术后,对照组给予常规治疗。观察组在常规治疗基础上联合应用生长抑素。比较两组患儿的腹围差、术后24h胃肠管引流和呕吐量、肛门排气时间、住院时间等术后情况;比较两组患儿术后并发症的发生率、生活质量评分,以及患儿和家长对治疗的满意度。结果观察组患儿的腹围差、24 h胃肠管引流和呕吐量、肛门排气时间及住院时间少于对照组(P0.05)。观察组患儿术后并发症发生率为6.7%,低于对照组患儿术后并发症发生率(18.3%)(P0.05)。两组患儿术前生活质量评分比较,差异无统计学意义(P0.05)。术后1个月,两组患儿的生活质量评分较术前提高(P0.05)。而且观察组患儿术后生活质量评分高于对照组(P0.05)。观察组患儿和家长对治疗的满意度为96.7%,高于对照组(81.7%)(P0.05)。结论小儿腹部手术后应用生长抑素能够有效促进患儿术后胃肠功能的恢复,改善预后,提高生活质量。
[Abstract]:Objective to evaluate the clinical efficacy and safety of somatostatin after abdominal surgery in children. Methods A total of 120 children with acute abdomen underwent abdominal surgery in Hainan Provincial people's Hospital from January 2014 to June 2016 were randomly divided into observation group (n = 60) and control group (n = 60). After abdominal operation, the control group was given routine treatment. The observation group was treated with somatostatin on the basis of routine therapy. The abdominal circumference, gastrointestinal tube drainage and vomiting, anal exhaust time and hospitalization time were compared between the two groups, and the incidence of postoperative complications and quality of life score were compared between the two groups. And the satisfaction of children and parents with the treatment. Results the amount of gastrointestinal tube drainage and vomiting, anal exhaust time and hospitalization time in the observation group were less than those in the control group (P0.05). The incidence of postoperative complications in the observation group was 6. 7%, which was lower than that in the control group (18. 3%) (P0.05). There was no significant difference in preoperative quality of life score between the two groups (P0.05). One month after operation, the scores of quality of life in the two groups were higher than those before operation (P 0.05). Moreover, the quality of life score in the observation group was higher than that in the control group (P0.05). The satisfaction of children and parents in the observation group was 96.7%, which was higher than that in the control group (81.7%) (P0.05). Conclusion the application of somatostatin after abdominal operation in children can effectively promote the recovery of gastrointestinal function, improve prognosis and improve the quality of life.
【作者单位】：海南省人民医院小儿外科;
【分类号】：R726.5

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