儿童嗜酸细胞性膀胱炎7例临床分析

发布时间：2018-08-25 14:17

【摘要】：目的探讨儿童嗜酸细胞性膀胱炎的临床、病理特点及诊断和治疗。方法回顾分析2012年至2016年收治的7例嗜酸细胞性膀胱炎患儿的临床资料,并复习相关文献。结果 7例患儿的中位年龄为9岁,临床表现为尿急、尿频、尿痛、血尿、下腹痛、夜间遗尿等。超声和CT检查示膀胱壁增厚和占位性病变。7例患儿通过膀胱活组织检查均符合嗜酸细胞性膀胱炎;6例患儿经药物治疗后在2个月内痊愈,另1例反复药物治疗1年痊愈。随访3个月~4年,排尿异常症状消失,影像学检查膀胱异常变化消失。结论儿童嗜酸细胞性膀胱炎为良性病变,与膀胱肿瘤的临床表现极为相似,确诊靠组织活检外,也可根据临床表现、实验室检查及治疗效果;治疗以激素、抗组胺、抗炎药物为主。
[Abstract]:Objective To investigate the clinical, pathological features, diagnosis and treatment of eosinophilic cystitis in children.Methods The clinical data of 7 children with eosinophilic cystitis admitted from 2012 to 2016 were analyzed retrospectively.Results The median age of the 7 children was 9 years old.The clinical manifestations were acute urination, frequent urination, urinary pain, hematuria, lower abdominal pain and nocturnal pain. Ultrasonography and CT showed thickening of bladder wall and space occupying lesions.7 cases of children with bladder biopsy were accorded with eosinophilic cystitis.6 cases were cured within 2 months after drug treatment,another case was cured after repeated drug treatment for 1 year.Follow-up for 3 months to 4 years,the abnormal urination symptoms disappeared and the abnormal changes of bladder were eliminated by imaging examination. Conclusion Eosinophilic cystitis in children is a benign lesion, which is very similar to the clinical manifestations of bladder tumor. The diagnosis depends on biopsy, clinical manifestations, laboratory examination and therapeutic effect. The treatment is mainly hormones, antihistamines and anti-inflammatory drugs.
【作者单位】：郑州大学第一附属医院;
【分类号】：R726.9

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