无水乙醇联合组织胶硬化栓塞儿童高回流静脉畸形临床疗效分析

发布时间：2018-09-17 14:01

【摘要】：目的探讨无水乙醇联合组织胶硬化栓塞治疗儿童高回流静脉畸形的临床效果。方法回顾性分析2009年4月至2014年10月全身麻醉下介入硬化剂治疗的339例静脉畸形患儿临床资料。对137例高回流静脉畸形患儿施行无水乙醇联合α-氰基丙烯酸正丁酯(NBCA)硬化栓塞治疗。术后随访6~24个月,平均15个月。结果 137例高回流静脉畸形患儿均成功接受无水乙醇联合NBCA胶治疗,其中23例治愈,31例基本治愈,42例有效(好转),总有效率为70%(96/137)。1例NBCA胶回流导致异位栓塞,8例皮肤破溃,3例术中出现一过性肺动脉高压,不良反应发生率为8%(12/137)。结论无水乙醇联合NBCA胶硬化栓塞治疗儿童高回流静脉畸形,是一种安全有效、不良反应发生率低的治疗方法。
[Abstract]:Objective To investigate the clinical effect of ethanol combined with tissue glue embolization in the treatment of hyperreflux venous malformations in children.Methods The clinical data of 339 children with venous malformations treated with interventional sclerotherapy under general anesthesia from April 2009 to October 2014 were retrospectively analyzed.137 children with hyperreflux venous malformations were treated with ethanol combined with alpha-cyanopropylene. Results 137 cases of high reflux venous malformations were successfully treated with absolute ethanol combined with NBCA glue. 23 cases were cured, 31 cases were basically cured, 42 cases were effective (improved). The total effective rate was 70% (96/137). One case of NBCA glue reflux led to ectopic embolism, 8 cases of skin ulceration, 3 cases of skin ulceration. The incidence of adverse reactions was 8%(12/137). Conclusion Ethanol combined with NBCA glue scleroembolization is a safe and effective method for the treatment of children with high reflux venous malformation.
【作者单位】：广州市妇女儿童医疗中心介入血管瘤科;
【基金】：广州市医药卫生科技一般引导项目(20141A011029)
【分类号】：R725.4

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