基于数据挖掘的临床检验项目与川崎病的关联性研究

发布时间：2018-11-27 19:57

【摘要】：目的:研究川崎病数据库中检验项目相关指标,挖掘检验结果与川崎病之间的关联规则,探讨相关检验结果与川崎病之间的关联性,为川崎病早期诊断、合理制定川崎病诊疗方案提供决策参考。方法:采用SQL Server 2008R2对川崎病数据进行预处理;选取诊断为川崎病的检验结果异常值总数较多的检验项目作为分析对象,提取诊断为非川崎病的同质检验项目作为对照,运用WEKA3.8.0分析临床检验项目与川崎病之间的关联性。结果:选取了川崎病患者5098例,非川崎病的患者726例;筛选出了43项检验相关指标纳入分析范围,挖掘出25条检验项目与川崎病之间的强关联规则。结论:川崎病多发于6岁以下男性儿童,1岁左右为高发期,PCT、ESR、Fib偏高会增加川崎病患病风险;检验结果值异常对早期诊断、合理制定川崎病临床诊疗方案有一定的指导意义。
[Abstract]:Objective: to study the correlation indexes of test items in Kawasaki disease database, to find the association rules between the test results and Kawasaki disease, and to explore the correlation between the test results and Kawasaki disease, so as to make the early diagnosis of Kawasaki disease. Rational formulation of Kawasaki disease diagnosis and treatment plan to provide decision-making reference. Methods: the data of Kawasaki disease were pretreated by SQL Server 2008R2. The test items with more abnormal values of Kawasaki disease were selected as the analysis object, and the homogeneous test items diagnosed as non-Kawasaki disease were selected as the control. WEKA3.8.0 was used to analyze the association between clinical test items and Kawasaki disease. Results: 5098 cases of Kawasaki disease and 726 cases of non-Kawasaki disease were selected, 43 items of test related indexes were selected into the scope of analysis, and the strong association rules between 25 test items and Kawasaki disease were excavated. Conclusion: Kawasaki disease is more common in male children under 6 years of age, with a high incidence of Kawasaki disease at about 1 year old. High PCT,ESR,Fib may increase the risk of Kawasaki disease. The abnormal value of test results has certain guiding significance for early diagnosis and rational formulation of clinical diagnosis and treatment of Kawasaki disease.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R725.4

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