医院儿科患儿感染病原菌分布及耐药性分析

发布时间：2019-04-27 01:44

【摘要】：目的分析医院儿科感染病原菌分布及耐药性,为临床合理用药提供参考依据。方法回顾性分析2015年医院住院治疗的120例感染患者临床病例资料,总结分析其病原菌感染分布情况及其耐药性,数据采用SPSS18.0软件进行统计分析。结果共培养出178株病原菌,其中革兰阳性菌93株占52.2%,革兰阴性菌80株占44.9%,真菌15株占8.4%,革兰阳性菌主要为金黄色葡萄球菌、凝固酶阴性葡萄球菌及溶血性葡萄球菌,分别占41.0%、5.1%及3.9%,革兰阴性菌主要为大肠埃希菌、肺炎克雷伯菌及铜绿假单胞菌,分别占26.4%、15.1%及4.5%;哌拉西林/他唑巴坦、头孢哌酮/舒巴坦、左氧氟沙星、阿米卡星、亚胺培南和美罗培南等抗菌药物的敏感性均较高。结论儿科病房内最常见的感染病原菌为革兰阳性菌,常见感染病原菌耐药性较严重,临床科室需高度重视,加强耐药性监测以及选取合理抗菌药物进行治疗。
[Abstract]:Objective to analyze the distribution and drug resistance of nosocomial paediatric infection pathogens and to provide reference for rational use of drugs in clinic. Methods the clinical data of 120 cases of infection in hospital in 2015 were retrospectively analyzed. The distribution of pathogen infection and its drug resistance were summarized and analyzed. The data were statistically analyzed by SPSS18.0 software. Results 178 strains of pathogenic bacteria were cultured, of which 93 were gram-positive bacteria (52. 2%), 80 were gram-negative bacteria (44. 9%), 15 were fungi (8. 4%), and the Gram-positive bacteria were mainly Staphylococcus aureus. Coagulase-negative staphylococcus and hemolytic staphylococcus accounted for 41.0%, 5.1% and 3.9% respectively. Gram-negative bacteria were mainly Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa, accounting for 26.4%, respectively. 15.1% and 4.5%; The sensitivity of piperacillin / tazobactam, cefoperazone / sulbactam, levofloxacin, amikacin, imipenem and meropenem was higher. Conclusion Gram-positive bacteria are the most common pathogens in paediatric ward. Drug resistance of pathogenic bacteria is very serious in pediatric ward. Clinical departments should pay more attention to drug resistance monitoring and select reasonable antimicrobial agents for treatment.
【作者单位】：浙江慈溪第三人民医院儿科;
【基金】：浙江省科技计划基金资助项目(KY2013-12)
【分类号】：R725.1

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