声脉冲辐射力成像技术对甲状腺良、恶性结节的鉴别诊断价值

发布时间：2018-06-12 09:24

本文选题：声脉冲辐射力成像技术 + 声触诊组织成像　；参考：《苏州大学》2014年硕士论文

【摘要】：1.研究目的：探讨声脉冲辐射力成像技术（Acoustic Radiation Force Impulse，ARFI）在甲状腺良、恶性结节鉴别诊断中的应用价值。 2.方法：选取2012年9月~2013年12月在本院进行诊治的甲状腺结节患者共80例，同时30例正常志愿者参与研究，列为对照组，对2组患者各病灶进行声触诊组织成像（Virtual touch tissue Imaging，，VTI）及声触诊组织定量（Virtual touch tissuequantification，VTQ）检测，获取相应的VTI值及不同甲状腺疾病的及周围组织的VTQ值，以术后病理为标准探讨AFRI技术在甲状腺疾病诊断中的应用价值，并分析患者满意度差异。 3.结果：良性结节53人，恶性结节27人，VTI结果显示，良性结节组显示为高回声占30.2%，说明肿块质地较软，显示为低回声占22.6%，说明肿块质地较硬，显示为等回声占47.2%，说明肿块质地软硬相当。恶性结节组显示为高回声占11.1%，显示为低回声占51.9%，显示为等回声占37%，说明恶性组结节以质地较硬者为主。VTQ结果显示，良性甲状腺结节组患者ARFI检测中的剪切波平均值明显低于恶性甲状腺结节组，具有显著性差异（P0.05），与正常组比较，明显高于正常组，具有显著性差异（P0.05）。甲状腺肿患者的剪切波速度明显高于甲状腺腺瘤和甲状腺增生，具有显著性差异（P0.05），甲状腺腺瘤与甲状腺增生比较没有显著性差异（P0.05）。恶性甲状腺结节中甲状腺乳头状癌的剪切波平均速度高于滤泡癌和髓样癌，具有显著性差异（P0.05），滤泡癌的剪切波平均速度高于髓样癌，具有显著性差异（P0.05）。ARFI检测满意度（97.5%）明显高于病理（66.3%）组，具有显著性差异（P0.05）。 4.结论：ARFI技术为甲状腺疾病的诊断提供了新的思路和理念，为传统的超声诊断方法做了补充，ARFI技术对甲状腺良、恶性结节的鉴别诊断具有一定的参考作用。
[Abstract]:1. Objective: to investigate the value of acoustic pulse radiation force imaging (ARFI) in differential diagnosis of benign and malignant thyroid nodules. Methods: from September 2012 to December 2013, 80 patients with thyroid nodules and 30 normal volunteers were selected as control group. All lesions in two groups were examined with Virtual touch tissue Imaging technique (VTI) and Virtual touch tissue Quantification (VTQs). The corresponding VTI values and the VTQ values of different thyroid diseases and surrounding tissues were obtained. To evaluate the value of AFRI technique in the diagnosis of thyroid diseases according to postoperative pathology, and to analyze the difference of patients' satisfaction. Results: there were 53 benign nodules and 27 malignant nodules. The results of VTI showed that the benign nodules were hyperechoic (30.2percent), which showed that the texture of the masses was soft, the hypoechoic masses were 22.66.It indicated that the masses were hard in texture. Isoechoic appearance accounted for 47.2%, indicating that the texture of the mass was equal to that of hard and soft. The malignant nodules were shown as hyperechoic (11.1%), hypoechoic (51.9%) and isoechoic (37%). The average value of ARFI in benign thyroid nodule group was significantly lower than that in malignant thyroid nodule group (P 0.05), and was significantly higher than that in normal group (P 0.05). The shear wave velocity of goiter was significantly higher than that of thyroid adenoma and thyroid hyperplasia (P 0.05), but there was no significant difference between thyroid adenoma and thyroid hyperplasia (P 0.05). The average shear wave velocity of papillary thyroid carcinoma was higher than that of follicular carcinoma and medullary carcinoma in malignant thyroid nodule (P 0.05), and the average shear wave velocity of follicular carcinoma was higher than that of medullary carcinoma. There was significant difference in the satisfaction degree of P0.05U. ARFI (97.5%) than in the pathological group (66.3%), and the difference was significant (P 0.05). 4. Conclusion the new idea and idea for the diagnosis of thyroid diseases are provided by the technique of ": ARFI", which provides a reference for the differential diagnosis of benign and malignant nodules of thyroid gland by supplementing the traditional ultrasonic diagnosis method. [WT5HZ] [WT5 "HZ] [WT5" HZ] [WT5 "HZ]
【学位授予单位】：苏州大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R736.1;R445.1

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