无锡地区不良妊娠结局妇女弓形虫感染及弓形虫病知识知晓率调查

发布时间：2017-12-31 01:23

本文关键词：无锡地区不良妊娠结局妇女弓形虫感染及弓形虫病知识知晓率调查　出处：《中国血吸虫病防治杂志》2016年06期 　论文类型：期刊论文

【摘要】：目的调查无锡地区不良妊娠结局妇女弓形虫感染情况及弓形虫病相关知识知晓率。方法以2011年1月至2015年12月无锡市217例不良妊娠结局妇女作为研究对象(试验组),以250例正常妊娠妇女作为对照。采用ELISA法检测并比较试验组和对照组血清抗弓形虫抗体阳性率。采用自行设计的问卷对试验组和对照组妇女进行问卷调查,比较两组弓形虫病相关知识知晓率。结果试验组妇女血清抗弓形虫抗体阳性率为30.88%,显著高于正常妊娠妇女的8.80%(χ~2=36.70,P0.01);抗弓形虫IgG和IgM抗体阳性率分别为20.74%和10.14%,显著高于对照组的6.00%和2.80%(χ~2=22.53和10.74,P均0.01)。此外,以胎停、自然流产、早产和出生缺陷为妊娠结局的妇女血清抗弓形虫抗体阳性率及血清抗弓形虫Ig G和Ig M抗体阳性率均显著高于正常妊娠妇女(P均0.05)。试验组妇女对"你听说过弓形虫或弓形虫病吗?"(P0.01)、"你知道养宠物猫和犬会感染弓形虫吗?"(P0.05)和"你知道孕期需要进行弓形虫感染检查吗?"(P0.01)等3道问题的知晓率显著低于对照组,而两组妇女对"你知道吃火锅会感染弓形虫吗?"、"你知道家中砧板生熟不分可能会导致弓形虫感染吗?"、"你知道孕妇感染弓形虫会传给胎儿吗?"、"你知道孕期弓形虫感染会导致流产、死胎、胎儿畸形等不良妊娠结局吗?"和"你知道孕妇感染弓形虫需要治疗吗?"等问题的知晓率差异无统计学意义(P均0.05)。结论无锡市地区不良妊娠妇女弓形虫感染率显著高于正常妊娠妇女。考虑到孕妇感染弓形虫的危害以及孕妇对弓形虫病相关知识知晓率较低的现状,应进一步加大弓形虫病相关知识宣传和健康教育力度,特别是对备孕妇女开展有针对性的弓形虫病健康教育,以降低孕妇弓形虫感染率、提高优生优育水平。
[Abstract]:Objective to investigate the prevalence of Toxoplasma gondii infection and knowledge of toxoplasmosis among women with adverse pregnancy outcomes in Wuxi from January 2011 to December 2015. Methods 217 women with adverse pregnancy outcomes in Wuxi from January 2011 to December 2015 were investigated. As an object of study (. Test group). The positive rate of anti-Toxoplasma gondii antibody in serum of the test group and the control group was detected and compared with that of the control group by ELISA method. The self-designed questionnaire was used to ask the women of the test group and the control group. Volume investigation. Results the positive rate of serum anti-Toxoplasma antibodies in the test group was 30.88, which was significantly higher than that in the normal pregnant women (8.80%) (蠂 2: 36.70). P0.01; The positive rates of IgG and IgM antibodies against Toxoplasma gondii were 20.74% and 10.14 respectively, which were significantly higher than those of the control group (6.00% and 2.80) (蠂 2, 22.53 and 10.74, respectively). P all 0.01. In addition, spontaneous abortion occurred when the fetus was stopped. The positive rates of serum anti-Toxoplasma gondii antibody and serum anti-Toxoplasma gondii IgG and IgM antibodies in women with preterm birth and birth defects were significantly higher than those in normal pregnant women (P 0.05). The women in the trial group said, "have you ever heard of toxoplasmosis or toxoplasmosis? "P0. 01," did you know that keeping a pet cat and dog can infect Toxoplasma gondii? "P0.05) and" do you know that Toxoplasma gondii infection needs to be tested during pregnancy? " The awareness rate of the three questions was significantly lower than that of the control group, and the two groups of women said, "do you know that eating hot pot will infect Toxoplasma gondii?" Do you know if the chopping board in your home is ripe or not, it can cause Toxoplasma gondii infection? Do you know that pregnant women infected with Toxoplasma can pass on to their fetuses? Do you know that Toxoplasma gondii infection during pregnancy can lead to miscarriage, stillbirth, fetal malformation and other adverse pregnancy outcomes? Do you know that pregnant women with Toxoplasma gondii need treatment? "there was no significant difference in the awareness rate between the two groups (P < 0.05). Conclusion the infection rate of Toxoplasma gondii in poor pregnant women in Wuxi is significantly higher than that in normal pregnant women, considering the harm of Toxoplasma gondii infection in pregnant women and the low knowledge rate of toxoplasmosis among pregnant women. In order to reduce the infection rate of Toxoplasma gondii in pregnant women, we should further increase the propaganda of Toxoplasma gondii related knowledge and health education, especially the health education for pregnant women, so as to reduce the infection rate of Toxoplasma gondii and raise the level of healthy birth and breeding.
【作者单位】：江苏省无锡市第九人民医院、苏州大学附属无锡九院;
【分类号】：R714.251
【正文快照】： 弓形虫是一种专性细胞内寄生的机会性致病原虫,可广泛感染人和动物,引起人兽共患弓形虫病[1]。弓形虫感染呈世界性分布,据估计全球约有1/3人口感染弓形虫[1]。由于宗教信仰、饮食习惯、社会经济发展水平不同,世界各地的弓形虫感染率差异较大,最高可达95%[2]。我国人群弓形虫感

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