戈舍瑞林联合曼月乐治疗子宫腺肌病的效果评价

发布时间：2018-01-04 12:01

本文关键词：戈舍瑞林联合曼月乐治疗子宫腺肌病的效果评价　出处：《中国当代医药》2016年34期 　论文类型：期刊论文

【摘要】：目的探讨戈舍瑞林联合曼月乐治疗子宫腺肌病的效果。方法将2014年2月~2015年2月在我院妇科治疗的70例子宫腺肌病患者随机分为观察组和对照组,每组各37例。对照组单用戈舍瑞林治疗,观察组采用戈舍瑞林联合曼月乐治疗。比较两组患者的治疗效果、子宫各项指标、痛经及月经改善情况;观察两组的不良反应。结果观察组治疗有效率为94.29%,显著高于对照组的85.71%,差异有统计学意义(P0.05);观察组治疗后子宫体积及子宫内膜厚度均明显小于对照组,差异有统计学意义(P0.05);观察组治疗后痛经程度评分及PBAC月经量评分均明显低于对照组,差异有统计学意义(P0.05);两组疲乏、骨痛、更年期症状、烦躁、阴道不规则流血、乳房胀痛等不良反应的总发生率比较差异无统计学意义(P0.05)。结论戈舍瑞林联合曼月乐治疗子宫腺肌病的效果显著,能够直接作用于子宫病灶,抑制子宫内膜的异常生长,减轻病灶活性,改善临床症状,有效避免了手术治疗,具有积极的临床意义。
[Abstract]:Objective to investigate the efficacy of goserelin combined with manyue in the treatment of adenomyosis. Methods 70 cases of adenomyosis treated in our hospital from February 2014 to February 2015 were randomly divided into observation group and control group. Group. There were 37 cases in each group. The control group was treated with goserelin alone, while the observation group was treated with goserelin combined with manyue. The therapeutic effect, uterine parameters, dysmenorrhea and menstrual improvement were compared between the two groups. Results the effective rate of treatment in the observation group was 94.29, which was significantly higher than that in the control group (85.71, P 0.05). The volume of uterus and the thickness of endometrium in the observation group were significantly lower than those in the control group after treatment, and the difference was statistically significant (P 0.05). After treatment, the scores of dysmenorrhea and PBAC menstrual volume in the observation group were significantly lower than those in the control group (P 0.05). Fatigue, bone pain, menopausal symptoms, irritability, irregular vaginal bleeding. There was no significant difference in the total incidence of adverse reactions such as breast distension and pain. Conclusion Gosherrelin combined with Manyuelo is effective in the treatment of adenomyosis and can directly affect uterine lesions. It has positive clinical significance to inhibit abnormal growth of endometrium, reduce focus activity, improve clinical symptoms and avoid surgical treatment.
【作者单位】：广东省惠东县妇幼保健院妇科;
【分类号】：R711.71
【正文快照】： 子宫腺肌病为临床育龄期妇女常见疾病,是指在多种因素的刺激下,子宫内膜腺体和间质侵入子宫肌层,造成弥漫性病变。本病呈进行性加重,临床表现为痛经、月经过多、贫血、性交痛等,B超检查可见子宫增大,严重者甚至发生不孕,影响正常生活和心理健康[1]。本病的治疗手段较多,其治疗

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