复方丹参片联合低分子肝素治疗对早发型重度子痫前期围产结局的影响

发布时间：2018-01-08 11:00

本文关键词：复方丹参片联合低分子肝素治疗对早发型重度子痫前期围产结局的影响　出处：《中国计划生育和妇产科》2016年12期 　论文类型：期刊论文

【摘要】：目的研究临床使用复方丹参片和低分子肝素对早发型重度子痫前期围产结局的影响。方法选取广东省妇幼保健院2013年10月至2015年10月收治的86例早发型重度子痫前期患者为研究对象,按照随机数字表法分为A组(48例)和B组(38例),两组患者均给予常规治疗,其中A组患者在常规治疗的基础上增加复方丹参片,B组患者在常规治疗的基础上联合使用低分子肝素和复方丹参片治疗,对比分析两组患者治疗效果及围产结局情况。结果两组患者围产结局中有不同程度的低蛋白血症、肝肾功能衰竭、视物障碍、胸腹水等并发症,B组患者并发症发生率(36.84%)低于A组(52.08%),两组患者均出现不同程度的胎儿宫内窘迫、新生儿窒息等症状,B组新生儿并发症发生率(34.21%)低于A组(45.83%),差异有统计学意义(P0.05);其中B组新生儿1min和5min Apgar评分优于A组(P0.05)。结论复方丹参片和低分子肝素联合使用能够有效改善早发型重度子痫前期患者围产结局,具有一定临床治疗价值。
[Abstract]:Objective to study the effect of compound Danshen tablets and low molecular weight heparin (LMWH) on perinatal outcome of early onset severe preeclampsia. Methods 8 cases of early onset severe preeclampsia were selected from October 2013 to October 2015 in Guangdong Maternal and Child Health Hospital. Six cases of early onset severe preeclampsia were studied. According to the random number table method, the patients in group A were divided into group A (n = 48) and group B (n = 38). The patients in group A were given routine treatment, and the patients in group A were treated with compound Danshen tablets on the basis of routine treatment. Patients in group B were treated with low-molecular-weight heparin and compound Danshen tablets on the basis of routine treatment. Results the perinatal outcome of two groups of patients with different degrees of hypoproteinemia, liver and kidney failure, visual disorders, hydrothorax and ascites, and other complications. The incidence of complications in group B (36.84) was lower than that in group A (52.08). The two groups had different degrees of fetal distress and neonatal asphyxia. The incidence of neonatal complications in group B (34.21) was lower than that in group A (45.83%), and the difference was statistically significant (P 0.05). The Apgar scores of newborns in group B were better than those in group A at 1 and 5 minutes (P 0.05). Conclusion compound Danshen tablets combined with low molecular weight heparin can effectively improve perinatal outcomes in patients with early onset severe preeclampsia. Has certain clinical treatment value.
【作者单位】：广东省妇幼保健院产科;
【分类号】：R714.244
【正文快照】： 早发型重度子痫前期是指孕妇妊娠晚期表现出的突然晕倒、牙关紧闭、四肢抽搐等子痫症状,在妊娠期高血压疾病中发病率约0.9%[1]。早发型重度子痫前期由于发病早、母体病情发展快、并发症重、新生儿孕周小、距离足月时间较久、出生后并发症多、存活率低,成为产科面临的难题。如

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