CKC术与LEEP术在治疗高级别宫颈鳞状上皮内病变的临床研究

发布时间：2018-01-08 11:17

本文关键词：CKC术与LEEP术在治疗高级别宫颈鳞状上皮内病变的临床研究　出处：《心血管病防治知识(学术版)》2016年12期 　论文类型：期刊论文

【摘要】：目的对比分析冷刀锥切术(CKC)与宫颈环形电锥切术(LEEP)治疗高级别宫颈鳞状上皮内病变的临床疗效。方法选取2015年5月至2016年5月期间在我科室进行治疗的高级别宫颈鳞状上皮内病变患者100例,入组研究对象按照所采取的手术治疗方式分为两组,即CKC组(n=50)和LEEP组(n=50)。CKC组患者行冷刀锥切术进行治疗,LEEP组患者行宫颈环形电锥切术进行治疗。结果 LEEP组患者的手术时间显著短于CKC组,LEEP组患者的术中出血量显著少于CKC组,比较差异具有统计学意义P0.05。CKC组和LEEP组患者的术后病灶残留率分别为2.0%和6.0%,比较差异不具有统计学意义P0.05;CKC组和LEEP组患者术后各个时间段的复发率相当,比较差异不具有统计学意义P0.05。CKC组和LEEP组患者术后各个时间段的HPV持续感染率相当,比较差异不具有统计学意义P0.05。CKC组和LEEP组患者的术后出血发生率分别为4.0%和2.0%,比较差异不具有统计学意义P0.05;CKC组和LEEP组患者的术后宫颈狭窄发生率分别为10.0%和4.0%,比较差异具有统计学意义P0.05。结论宫颈环形电锥切术治疗高级别宫颈鳞状上皮内病变交冷刀锥切术有明显的优势,可作为高级别宫颈鳞状上皮内病变临床治疗的首选治疗方式。
[Abstract]:Objective to compare and analyze CKCX (cold knife coning) and LEEP (circular electroconization of cervix cervix). Methods from May 2015 to May 2016, 100 patients with high grade cervical squamous intraepithelial lesions were treated in our department. The subjects were divided into two groups according to the surgical treatment: CKC group (n = 50) and LEEP group (n = 50). Results the operative time of LEEP group was significantly shorter than that of CKC group and that of CKC group was significantly less than that of CKC group. The difference was statistically significant (P 0.05) between CKC group and LEEP group (P 0.05). The residual rates of postoperative lesions were 2.0% and 6.0 respectively in CKC group and LEEP group, but the difference was not statistically significant (P0.05). The recurrence rates of CKC group and LEEP group were similar at every time after operation. There was no significant difference between the two groups (P0.05. CKC group and LEEP group). The persistent infection rate of HPV was the same in each period of time after operation in CKC group and LEEP group. The incidence of postoperative hemorrhage in CKC group and LEEP group was 4.0% and 2.0 respectively, but the difference was not statistically significant (P0.05). The incidence of postoperative cervical stenosis in CKC group and LEEP group was 10.0% and 4.0% respectively. The difference was statistically significant (P0.05.Conclusion Cervical circular electroconization has obvious advantages in the treatment of high-grade cervical squamous intraepithelial lesions. It can be used as the first choice in the treatment of high grade cervical squamous intraepithelial lesions.
【作者单位】：福建医科大学附属泉州第一医院;
【分类号】：R737.33
【正文快照】： 宫颈癌是一种常见的妇科恶性肿瘤疾病,对女性的生命健康具有极大的危害。临床研究表明,宫颈上皮内瘤变(CIN)是一组与宫颈癌发病具有密切相关的子宫颈病变,反映了宫颈癌的发生、发展中的连续过程[1]。临床上将CIN I划分为低级别宫颈鳞状上皮内病变(LSIL),将CIN II-III划分为高

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