动态血糖在妊娠期糖尿病患者胰岛素强化治疗期间的临床应用价值

发布时间：2018-01-13 10:26

本文关键词：动态血糖在妊娠期糖尿病患者胰岛素强化治疗期间的临床应用价值　出处：《重庆医学》2015年36期 　论文类型：期刊论文

【摘要】：目的探讨连续动态血糖监测(CGMS)在妊娠期糖尿病(GDM)患者胰岛素强化治疗期间的临床应用价值。方法随机选取2013年3月至2014年2月本院门诊妊娠期糖尿病筛查确诊的GDM患者65例,均采取胰岛素泵持续皮下输注胰岛素(CSII)治疗,随机分为CGMS组(n=34)和指血监测组(n=31)。结果两组患者血糖均于餐前明显降低,餐后明显升高,波动幅度均较大,并均于睡前至早餐前血糖趋于稳定,波动幅度较小。两组患者均达相同强化血糖目标值,CGMS组患者治疗期血糖平均值明显低于指血监测组(P0.05);CGMS组患者血糖达标时间明显短于指血监测组(P0.05);两组患者治疗期间胰岛素剂量比较差异无统计学意义(P0.05);CGMS组患者治疗期间低血糖发生次数明显低于指血监测组(P0.05);CGMS组患者新生儿低血糖、高胆红素血症的发生率明显低于指血监测组(P0.05)。结论应用CGMS监测GDM患者血糖变化,有利于临床医师针对患者血糖动态变化趋势制订个体化用药方案,进而有效改善患者母儿预后。
[Abstract]:Objective to investigate the effect of continuous glucose monitoring (CGMS) in gestational diabetes mellitus (GDM) during intensive therapy, the clinical application value of insulin. 65 GDM patients were randomly selected from March 2013 to February 2014 in the outpatient screening of diabetes mellitus during pregnancy diagnosed cases, adopt continuous subcutaneous insulin infusion (CSII) therapy, were randomly divided into CGMS group (n=34) and the blood monitoring group (n=31). The results of two groups of patients with blood glucose levels were significantly lower in before meals, after meals increased significantly, fluctuations are large, and before going to bed before breakfast to blood sugar stable, wave amplitude is smaller. Two groups of patients were the same as intensive blood glucose target, CGMS group treatment of patients with blood glucose was significantly lower than the average value of finger blood monitoring group (P0.05); group CGMS blood glucose time was shorter than the finger blood monitoring group (P0.05); the two groups of patients during treatment with insulin dose was no significant difference (P0. 05); group CGMS patients during the treatment of hypoglycemia was significantly lower than that of monitoring blood group (P0.05); CGMS group of patients with neonatal hypoglycemia, hyperbilirubinemia incidence was significantly lower than that of monitoring blood group (P0.05). Conclusion the changes of blood glucose of patients monitored by CGMS GDM, and help clinicians individualized treatment programs for patients with dynamic changes in blood glucose trends then, effectively improve the patient's prognosis.

【作者单位】：江苏省南京市第一医院内分泌科;
【分类号】：R714.256
【正文快照】： 病率呈逐年上升趋势,占妊娠期糖代谢紊乱的90%[1]。GDM可使母体并发高血压、羊水过多、糖尿病眼病等严重并发症,同时还可能导致胎儿生长受限、发育异常、甚至死亡等,严重影响孕妇的产后健康和新生儿预后[2]。血糖监测是诊断GDM、制订个体化血糖控制方案、监护母体和胎儿安危的

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