MRI诊断胎儿泌尿系统异常:Meta分析

发布时间：2018-01-14 12:10

本文关键词：MRI诊断胎儿泌尿系统异常:Meta分析　出处：《中国医学影像技术》2015年11期 　论文类型：期刊论文

【摘要】：目的应用Meta分析探讨MRI作为超声补充检查诊断胎儿泌尿系统异常的价值。方法检索1991年1月—2014年11月Pubmed、Elsevier-SDOL(Science Direct OnLine)、中国知网(CNKI)检索平台、万方数据库、维普期刊数据库及中国生物医学文献数据库中,对超声怀疑泌尿系统异常的胎儿行MRI检查并评估其诊断价值的相关文献。采用QUADAS-2评分标准评价文献质量,采用Metadisc1.4软件分析诊断的特异度、敏感度、阳性似然比及阴性似然比,并绘制汇总受试者工作特征(SROC)曲线,计算曲线下面积(AUC)。结果共纳入9篇文献。对存在异质性的阳性似然比采用随机效应模型进行效应量合并。Meta分析显示,MRI诊断胎儿泌尿系统异常的汇总敏感度、汇总特异度、汇总阳性似然比、汇总阴性似然比及各自95%CI分别为0.96(95%CI 0.93~0.98)、0.75(95%CI 0.57~0.88)、2.98(95%CI 1.05~8.45)、0.07(95%CI 0.04~0.13)。SROC曲线的AUC为0.96。结论 MRI作为超声补充检查诊断胎儿泌尿系统异常具有较高的价值。
[Abstract]:Objective to evaluate the value of MRI as an ultrasound supplementary examination in the diagnosis of fetal urinary system abnormalities by Meta analysis. Methods Pubmed was searched from January 1991 to November 2014. Elsevier-SDOL(Science Direct Online, CNKI, Wanfang Database. In the WIP journal database and the Chinese biomedical literature database. MRI examination and evaluation of the diagnostic value of ultrasound for fetuses with suspected urinary system abnormalities. The quality of the literature was evaluated by QUADAS-2 scoring criteria. The specificity, sensitivity, positive likelihood ratio and negative likelihood ratio of diagnosis were analyzed by Metadisc1.4 software. The area under the curve was calculated and the area under the curve was calculated. The results were included in 9 articles. The positive likelihood ratio with heterogeneity was analyzed by random effect model combined with meta-analysis. Summary sensitivity, specificity and positive likelihood ratio of MRI in diagnosing fetal urinary system abnormalities. The total negative likelihood ratio and 95 CI were 0.96 卤95CI 0.930.98 and 0.7595 CI 0.570.88, respectively. 2.98 / 95 / CI 1.05 / 8.45). The AUC of 0.07 / 95 CI 0.04 0.13C curve is 0.96.Conclusion MRI is of high value in the diagnosis of fetal urinary system abnormalities as an ultrasound supplementary examination. [WT5HZ] [WT5 "HZ] [WT5" BZ] [WT5 "BZ]
【作者单位】：暨南大学附属第一医院医学影像中心;
【基金】：广东省科技计划项目(2013B051000058)
【分类号】：R715.5;R445.2
【正文快照】： 图1 MRI诊断胎儿泌尿系统异常的森林图A.汇总敏感度(sensitivity);B.汇总特异度(specificity);C.阳性似然比(positive LR);D.阴性似然比(negative LR)研究[1-2]显示,胎儿泌尿生殖系统异常发生率约为0.1%~1.0%,产前超声检查(ultrasonography,US)能发现14%~40%。US为评估胎儿情

【参考文献】