妊娠期高血压疾病住院患者用药分析

发布时间：2018-01-15 23:09

  本文关键词：妊娠期高血压疾病住院患者用药分析　出处：《中国临床药理学杂志》2017年16期 　论文类型：期刊论文

  更多相关文章： 妊娠期高血压疾病 住院患者 用药分析 循证药学

【摘要】：目的回顾性分析妊娠期高血压疾病住院患者的用药情况,分析其用药合理性。方法收集该医院产科2011年1月至2015年6月主要诊断为妊娠期高血压疾病的住院患者基本资料、用药信息和费用信息,用SPSS22.0软件对数据进行统计分析。结果共纳入妊娠期高血压疾病住院患者974例,其中,重度子痫前期患者最多,占38.81%(378/974例)。对使用药物进行分析,共包括降压药物4种、防治子痫药物3种、镇静药物3种、利尿剂、纠正低蛋白血症药物和中成药各1种。各亚组用药情况略有差异。使用频次前10位的药品为维生素C、维生素E、硝苯地平、川芎嗪、硫酸镁、硝苯地平缓释片、白蛋白、地西泮片、乌拉地尔和呋塞米。结论妊娠期高血压疾病住院患者的药物治疗是以防治子痫前期和降压为主,同时中成药川芎嗪联合使用,符合疾病诊疗指南用药要求,用药基本合理。但维生素C和维生素E的使用存在争议。
[Abstract]:Objective to analyze the drug use of hypertensive disorder complicating pregnancy inpatients retrospectively. Methods from January 2011 to June 2015, we collected the basic data, medication information and cost information of the inpatients who were mainly diagnosed as hypertensive disorder complicating pregnancy in the hospital from January 2011 to June 2015. SPSS22.0 software was used to analyze the data. Results 974 patients with hypertensive disorder complicating pregnancy were included in the study. The most of them were severe preeclampsia. 38.81% 37.8% 974 cases were analyzed, including 4 kinds of antihypertensive drugs, 3 kinds of anti-eclampsia drugs, 3 kinds of sedatives and diuretics. There was a slight difference between the two subgroups. The top 10 drugs were vitamin C, vitamin E, nifedipine, ligustrazine and magnesium sulfate. Nifedipine sustained release tablets, albumin, diazepam tablets, urapidil and furosemide. Conclusion the main drug treatment for hypertensive disorder complicating pregnancy is preeclampsia and hypotension. Meanwhile, the combination of ligustrazine and traditional Chinese patent medicine meets the requirements of diagnosis and treatment of diseases and is reasonable, but the use of vitamin C and vitamin E is controversial.
【作者单位】： 山东大学第二医院产科;山东大学临床医学院;山东大学第二医院药学部;山东大学第二医院循证医学中心;山东大学第二医院信息中心;山东大学第二医院病案室;山东大学公共卫生学院;
【基金】：山东省自然科学基金资助项目(ZR2014HP029)
【分类号】：R714.246
【正文快照】： (1.山东大学第二医院,a.产科;b.药学部;c.循证医学中心;d.信息中心;e.病案室,济南250033;2.山东大学,a.临床医学院;b.公共卫生学院,济南250012)YAN Chun-mei1a,2a,ZOU Wen1b,HONG Fan-zhen1a,XU Yong-ping1a,JIA Hong-ying1c,LIU Huan-di1d,ZHANG Ying-hui1e,XIAO Juan1c,ZHAN，

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