不同剂量垂体后叶素对腹腔镜子宫肌瘤剔除术中循环的影响

发布时间：2018-01-16 11:39

本文关键词：不同剂量垂体后叶素对腹腔镜子宫肌瘤剔除术中循环的影响　出处：《中国肿瘤临床与康复》2013年08期 　论文类型：期刊论文

【摘要】：目的探讨不同剂量垂体后叶素对量对腹腔镜子宫肌瘤剔除术中循环系统的影响。方法将100例腹腔镜子宫肌瘤剔除术患者随机分为A组和B组,A组患者给予垂体后叶素6 U在子宫肌层进行注射,B组患者给予垂体后叶素12 U在子宫肌层进行注射,观察两组患者手术情况及不同时间段心率(HR)、血压(BP)、血氧饱和度(SpO2)变化情况。结果两组患者手术时间,术中出血量、血红蛋白下降水平、术后排气时间、术后住院时间差异均无统计学意义(均P0.05),两组患者HR和DBP在注射后3、4和5 min均有明显升高,HR在8 min和10 min明显下降,与注射后1 min水平比较,差异均有统计学意义(P0.05),并且A组HR在5 min水平明显低于B组,差异有统计学意义(P0.05),两组患者SBP在注射后3 min开始升高,且B组患者升高水平明显高于A组,差异有统计学意义(P0.05)。结论腹腔镜子宫肌瘤剔除术应用小剂量垂体后叶素能有效减少术中出血量,并避免剧烈的循环波动,值得临床推广应用。
[Abstract]:Objective to investigate the effect of different doses of pituitrin on the circulatory system during laparoscopic hysteromyomectomy. Methods 100 patients with laparoscopic hysteromyomectomy were randomly divided into group A and group B. The patients in group A were injected with 6 U pituitrin in the myometrium of uterus. Group B was injected with 12 U pituitrin in the myometrium of uterus. The changes of heart rate (HRP), blood pressure (BP) and oxygen saturation (SPO _ 2) in the two groups were observed. Results the operation time and blood loss during operation were observed in the two groups. There was no significant difference in hemoglobin level, postoperative exhaust time and postoperative hospitalization time (all P 0.05). HR and DBP were significantly increased in the two groups at 3 ~ 4 and 5 min after injection. HR decreased significantly at 8 min and 10 min, compared with 1 min after injection, the difference was statistically significant (P 0.05). The level of HR in group A was significantly lower than that in group B at 5 min, the difference was statistically significant (P 0.05). The level of SBP in two groups began to increase 3 min after injection. The level of elevation in group B was significantly higher than that in group A. the difference was statistically significant (P 0.05). Conclusion Laparoscopic hysteromyomectomy with low dose of pituitrin can effectively reduce the amount of intraoperative bleeding. And avoid violent cycle fluctuation, worthy of clinical popularization and application.
【作者单位】：新疆医科大学附属肿瘤医院麻醉科;
【基金】：新疆医科大学科研创新基金;编号:X3C201259
【分类号】：R737.33
【正文快照】： 腹腔镜子宫肌瘤剔除术因其疗效确切、手术创伤小和美观等优点而广泛应用于临床[1],但是,子宫血运丰富,剔除肌瘤过程中常常发生出血情况,出血不但会增加术后并发症的发生,而且会使术野暴露不清,增加手术难度,甚至导致手术失败[2]。因此,临床中常局部注射垂体后叶素,加强子宫收

【参考文献】