门冬氨酸钾与氯化钾对老年妇科恶性肿瘤患者围术期恢复影响的比较

发布时间：2018-01-17 17:02

本文关键词：门冬氨酸钾与氯化钾对老年妇科恶性肿瘤患者围术期恢复影响的比较　出处：《中国老年学杂志》2015年12期 　论文类型：期刊论文

【摘要】：目的探讨门冬氨酸钾对老年妇科恶性肿瘤患者围术期恢复的影响。方法选择妇科100例需行手术治疗的老年肿瘤患者,随机分为试验组和对照组每组50例,给予试验组患者含有门冬氨酸钾的静脉营养,对照组含有氯化钾的静脉营养液,分别比较两组手术前后血常规、尿常规及肝肾功能。结果手术前两组患者血钾、年龄、肿瘤分期等没有差异,血白细胞增加率较对照组减少13.3%,谷草转氨酶含量下降率小于对照组,试验组尿素产生量明显高于对照组,试验组患者恢复情况强于对照组(均P0.05)。结论门冬氨酸钾可提高老年围术期患者免疫力,抑制感染,促进患者恢复,具有较高临床应用价值。
[Abstract]:Objective to investigate the effect of potassium aspartate on the perioperative recovery of elderly gynecological malignant tumors. Methods 100 elderly patients with gynecological malignancy were randomly divided into two groups: the experimental group and the control group. The patients in the test group were given potassium aspartate intravenous nutrition, and the control group were given the intravenous nutrient solution of potassium chloride. Blood routine, urine routine and liver and kidney function were compared before and after operation. Results before the operation, the patients in the two groups were treated with potassium. There was no difference in age, tumor stage and so on. The increase rate of white blood cells was decreased by 13.3%, the decrease rate of glutamic oxaloacetic transaminase content was lower than that of the control group, and the urea production in the test group was significantly higher than that in the control group. Conclusion potassium aspartate can improve immunity, inhibit infection and promote recovery of elderly patients during perioperative period, which has high clinical application value.
【作者单位】：中国医科大学附属盛京医院妇产科;
【基金】：国家科技部十二五“重大新药创制”科技重大专项课题(2012ZX09401004) 辽宁省自然科学基金(20102255) 辽宁省科学技术计划项目(2012225017)
【分类号】：R737.3
【正文快照】： 世界卫生组织(WHO)预计至2020年,全球将有1 500万人被诊断癌症,1 000万人死于癌症〔1〕,老年妇科恶性肿瘤患者年龄大,因生理功能退化,基础疾病多,如高血压、心脑血管疾病、糖尿病、器官功能减退等,术后伤口容易感染、愈合不良;对手术刺激应激能力下降,伴随许多慢性病,术中易渗

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